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Cat. No.: HY-W903631

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SB-216641

SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations.

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CAS No.: 170230-39-4
화학식: C₂₈H₃₀N₄O₄
분자량:486.56

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SB-216641 Chemical Structure

CAS No.: 170230-39-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations^[1]^[2].

IC₅₀ & Target^[1]^[2]

5-HT_1B Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 170230-39-4
분자량 486.56
화학식 C₂₈H₃₀N₄O₄
SMILES

O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Taylor R M, et al. Systemic Administration of the 5-HT1b Antagonist SB-216641 Prior to Acute Stress Exposure in Rats Mildly Prevents Stress-induced Behavioral Performance Dysregulations[J]. The Journal of Pharmacology and Experimental Therapeutics, 2024, 389: 115.

[2]. Price GW, et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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SB-216641

High-Throughput Bioactive Compound Library

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

SB-216641 Related Classifications

HY-W903631 Related Classifications