Solavetivone
Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection.
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- CAS No.: 54878-25-0
- 화학식: C15H22O
- 분자량:218.33
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CYP76A2L |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| OVCAR-3 | IC50 |
0.1 mM
Compound: 1, Solavetivone
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Cytotoxicity against human OVCAR-3 cells
Cytotoxicity against human OVCAR-3 cells
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[PMID: 11575964] |
Solavetivone (3.2-16.1 μg/mL; 48 h) inhibits in vitro mycelial growth of Rhizoctonia solani in a concentration-dependent manner, with 27.6% inhibition observed at 16.1 μg/mL after 48 h incubation[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 54878-25-0
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분자량 218.33
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화학식 C15H22O
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SMILES
C[C@H]1[C@@]2(C(C)=CC(C1)=O)C[C@@H](CC2)C(C)=C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Camagna M, et al. Detoxification of the solanaceous phytoalexins rishitin, lubimin, oxylubimin and solavetivone via a cytochrome P450 oxygenase. Plant Signal Behav. 2020;15(2):1707348. [Content Brief]
[3]. Yao MK, et al. Effect of mycorrhization on the accumulation of rishitin and solavetivone in potato plantlets challenged with Rhizoctonia solani. Mycorrhiza. 2003;13(6):333-336. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Solavetivone Related Classifications
HY-N12475 Related Classifications
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- Solavetivone
- 54878-25-0
- Fungal
- Cytochrome P450
- sesquiterpenoid phytoalexins hydroxylase
- Glomus etunicatum
- Hyoscyamus muticus
- calcium-alginate immobilized Hyoscyamus muticus cells
- Solanum plants
- Rhizoctonia solani
- Nicotiana benthamiana
- SPH/CYP76A2L
- Solanum tuberosum cv. Goldrush
- potato roots
- Inhibitor
- inhibitor
- inhibit