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Cat. No.: HY-182452

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U 84569

U 84569 is a potent low-Km cAMP-dependent Phosphodiesterase inhibitor, with an IC₅₀ value of 300 nM in platelet cytosol. By inhibiting phosphodiesterase and elevating cAMP levels, U 84569 indirectly blocks receptor-mediated Phospholipase C activation, thereby inhibiting platelet aggregation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 130736-25-3
화학식: C₂₅H₂₃NO₄
분자량:401.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

U 84569 Chemical Structure

CAS No.: 130736-25-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Protocol (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

PLC

All Phosphodiesterase (PDE) Isoforms :

All Phospholipase Isoforms :

Chemical Information

CAS No. 130736-25-3
분자량 401.45
화학식 C₂₅H₂₃NO₄
SMILES

O=C1C=C(N2CCOCC2)OC3=C(C)C(OCC4=CC=CC5=C4C=CC=C5)=CC=C31
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Benjamin CW, et al. 2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity. J Pharmacol Exp Ther. 1993 Apr;265(1):457-62. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Protocol
순도&문서
References

상품명:
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U 84569

All Phosphodiesterase (PDE) Isoforms

All Phospholipase Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

Protocol

순도&문서

References

Calculators

Help & FAQs

U 84569 Related Classifications

HY-182452 Related Classifications

Bioz

Keywords

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