Paynantheine
Paynantheine is an alkaloid with antinociceptive activity, which is found in Mitragyna speciosa. Paynantheine is also a 5-HT1AR and 5-HT2BR agonist that induces lower lip retraction and antinociception in rats.
For research use only. We do not sell to patients.
- CAS No.: 4697-66-9
- Formula: C23H28N2O4
- Molecular Weight:396.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1A Receptor |
5-HT2B Receptor |
Chemical Information
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CAS No. 4697-66-9
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Molecular Weight 396.48
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Formula C23H28N2O4
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SMILES
COC1=C2C3=C(NC2=CC=C1)[C@@]4([H])N(C[C@@H]([C@H](C4)/C(C(OC)=O)=C\OC)C=C)CC3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Philipp AA, et al. Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879(15-16):1049-55. [Content Brief]
[2]. León F, et al. Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors. J Med Chem. 2021 Sep 23;64(18):13510-13523. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Paynantheine Related Classifications
HY-124412 Related Classifications
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