1. PI3K/Akt/mTOR
  2. PI3K
  3. PI3K-IN-28

PI3K-IN-28 

Cat. No.: HY-145432
Handling Instructions

PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents.

For research use only. We do not sell to patients.

PI3K-IN-28 Chemical Structure

PI3K-IN-28 Chemical Structure

CAS No. : 2747100-02-1

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Description

PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents[1].

Molecular Weight

653.54

Formula

C26H16F9N3O3S2

CAS No.
SMILES

O=S(OC1=CC=C(C=C1)/C=N/N=C2SC=C(N\2C3=CC=CC=C3)C4=CC=CC=C4)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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