PPARγ agonist-21

PPARγ agonist-21 (Compound 9a) is a PPARγ agonist with an EC50 of 3.12 μM. PPARγ agonist-21 activates PPAR-γ to inhibit NF-κB and attenuate NLRP3 inflammasome assembly. PPARγ agonist-21 blocks NLRP3-ASC and NLRP3-NEK7 interaction. PPARγ agonist-21 attenuates the severity of gouty arthritis.

For research use only. We do not sell to patients.

  • Formula: C19H17BrN2O5
  • Molecular Weight:433.25
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All NOD-like Receptor (NLR) Isoforms

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All NEKs Isoforms

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100 mg

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