1. PROTAC
    Epigenetics
  2. PROTAC
    Epigenetic Reader Domain
  3. PROTAC BRD4 Degrader-14

PROTAC BRD4 Degrader-14 

Cat. No.: HY-138637
Handling Instructions

PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

For research use only. We do not sell to patients.

PROTAC BRD4 Degrader-14 Chemical Structure

PROTAC BRD4 Degrader-14 Chemical Structure

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Description

PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells[1].

Molecular Weight

1150.27

Formula

C₅₇H₆₁F₂N₉O₁₁S₂

SMILES

O[[email protected]](C[[email protected]]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)CN1C([[email protected]@H](NC(COCCC4=CC(OCCNC(C5=CC(N(C6=NC=C(F)C=C6F)CC7=CNC8=C7C9=CN(C)C8=O)=C9C=C5CS(=O)(C)=O)=O)=CC(O)=C4)=O)C(C)(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

PROTAC BRD4 Degrader-14PROTACEpigenetic Reader DomainProteolysis-targeting chimeraBD1PC3prostatecancerInhibitorinhibitorinhibit

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Product Name:
PROTAC BRD4 Degrader-14
Cat. No.:
HY-138637
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