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Recilisib sodium

(Synonyms: ON 01210 sodium)
45 Cited Publications
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Based on 45 publication(s) in Google Scholar

Recilisib sodium (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells.

For research use only. We do not sell to patients.

  • CAS No.: 922139-31-9
  • Formula: C16H12ClNaO4S
  • Molecular Weight:358.77
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Recilisib sodium Chemical Structure
    Recilisib sodium Chemical Structure
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
  • Experimental Validation Results for Recilisib sodium
CAS No.: 922139-31-9
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  • Recilisib sodium Chemical Structure
    Recilisib sodium Chemical Structure
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    Recilisib sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Feb 12:139:156464. [Abstract]

    Customer Validation
     Recilisib significantly reversed BRU-induced suppression of lipid metabolism in 143B, U2OS cells.

  • 1/16

    Recilisib sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2024 Sep 7:135:156022. [Abstract]

    Customer Validation
     Recilisib partially reversed the proliferation inhibitory effect of HA in RBE and HuccT1 cells.

  • 1/16

    Recilisib sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2024 Sep 7:135:156022. [Abstract]

    Customer Validation
     Recilisib indeed elevated the protein expression of P-mTOR (Ser2448), P-PI3K (Tyr607), and P-AKT (S473) following HA-induced inhibition PI3K-AKT-mTOR activator recilisib reversed the effect of HA on ICC.

  • 1/16

    Recilisib sodium purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2023 May;13(5):463-482. [Abstract]

    Customer Validation
     Recilisib (10 μM) activated the PI3K/AKT pathway (via recilisib), leading to an increased HCC cell viability in the cotreatment group compared to the Rk3 only group.

  • 1/16

    Recilisib sodium purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2023 May;13(5):463-482. [Abstract]

    Customer Validation
     Recilisib (10 μM) increased the protein expression of CDK4, cyclin D1 and P62, as well as decreased the protein expression of Bax, c-PARP and LC3II/LC3I in HepG2 and HCC-LM3 cells with 100 μM Rk3.

  • 1/16

    Recilisib sodium purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2020 Mar 15;147:79-88. [Abstract]

    Customer Validation
     Measurement of ERK1/2 and NF-κB p65. Effect of GFP-A and Recilisib (activator of Akt) (10 μmol/L) on the expression of phosphorylated ERK1/2 in HT-29 cells. Cells are treated with 180 μg/mL GFP-A in the presence or absence of Recilisib for different durations of time.

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    Recilisib sodium purchased from MedChemExpress. Usage Cited in: Environ Toxicol. 2020 Dec;35(12):1299-1307. [Abstract]

    Customer Validation
     FaDu cells with AGK overexpression is treated with the PI3K inhibitor LY294002, and Cal27 cells with AGK knockdown is treated with PI3K activator Recilisib (50 μM). The inhibitory effect of LY294002 and promoting effects of Recilisib on PI3K/Akt signaling is confirmed by Western blot analysis.

  • Recilisib sodium