(S)-NSD2-IN-5
Based on 1 Customer Validation
(S)-NSD2-IN-5 is the S-isomer of NSD2-IN-5 (HY-177499). NSD2-IN-5 is an NSD2 inhibitor with an IC50 value between 0.001 μM and 0.01 μM. NSD2-IN-5 can be used in cancer research.
For research use only. We do not sell to patients.
- Formula: C27H25F2N9
- Molecular Weight:513.54
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Histone Methyltransferase Isoforms
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Biological Activity
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NSD2 |
Chemical Information
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Appearance Solid
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Molecular Weight 513.54
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Formula C27H25F2N9
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SMILES
FC(C=C1C2=NC=C(N3CCC[C@](N)(C3)C4=CC=CC=N4)C(CN5C6=NC=NC(N)=C6N=C5)=C2)=C(C=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (194.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9473 mL | 9.7363 mL | 19.4727 mL | 48.6817 mL |
| 5 mM | 0.3895 mL | 1.9473 mL | 3.8945 mL | 9.7363 mL | |
| 10 mM | 0.1947 mL | 0.9736 mL | 1.9473 mL | 4.8682 mL | |
| 15 mM | 0.1298 mL | 0.6491 mL | 1.2982 mL | 3.2454 mL | |
| 20 mM | 0.0974 mL | 0.4868 mL | 0.9736 mL | 2.4341 mL | |
| 25 mM | 0.0779 mL | 0.3895 mL | 0.7789 mL | 1.9473 mL | |
| 30 mM | 0.0649 mL | 0.3245 mL | 0.6491 mL | 1.6227 mL | |
| 40 mM | 0.0487 mL | 0.2434 mL | 0.4868 mL | 1.2170 mL | |
| 50 mM | 0.0389 mL | 0.1947 mL | 0.3895 mL | 0.9736 mL | |
| 60 mM | 0.0325 mL | 0.1623 mL | 0.3245 mL | 0.8114 mL | |
| 80 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6085 mL | |
| 100 mM | 0.0195 mL | 0.0974 mL | 0.1947 mL | 0.4868 mL |