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SAL-0010042

SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase β (PDEβ), that inhibits the hydrolysis of cAMP and cGMP (IC50=48.9 nM) in gametocytes, activates PKG, and inhibits the growth and development of Plasmodium (IC50 for 3D7 and Dd2 is 142 nM and 218 nM). SAL-0010042 inhibits hPDE5 and hPDE6 with IC50 of 632 nM and 73 nM.

For research use only. We do not sell to patients.

  • CAS No.: 521298-46-4
  • Formula: C15H15FN4O
  • Molecular Weight:286.30
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SAL-0010042 Chemical Structure
    SAL-0010042 Chemical Structure
CAS No.: 521298-46-4
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Top Publications Citing

Use of MCE Products

All Phosphodiesterase (PDE) Isoforms

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All Parasite Isoforms

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100 mg

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  • SAL-0010042 Chemical Structure
    SAL-0010042 Chemical Structure
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  • SAL-0010042