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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
314 Results for "
branches
" in MedChemExpress (MCE) Product Catalog:
Products (314)
314 Results for "branches" in MCE Product Catalog:
19
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9
9 Cited Publications
Cat. No.: HY-W250110
CAS No.: 9002-98-6
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Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH .
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9 Cited Publications
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BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) . BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM .
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7 Cited Publications
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BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema .
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Endocrine diseases Amino acids Plants Other Families Extract Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Other Diseases Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder
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7
7 Cited Publications
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BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm .
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7 Cited Publications
7
7 Cited Publications
Cat. No.: HY-W127715
CAS No.: 71206-95-6
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5 Cited Publications
Cat. No.: HY-N0486S9
CAS No.: 87828-86-2
5
5 Cited Publications
Cat. No.: HY-W193545A
CAS No.: 1415683-79-2
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ERG240 is an oral active branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. ERG240 can be used for the research of cancer, rheumatoid arthritis, and bone disease .
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4 Cited Publications
Synonyms: Z-Pro-D-Leu-OH
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Netupitant (CID 6451149) is a blood-brain barrier penetrable, orally active NK1 receptor inhibitor with a Ki of 0.95 nM (CHO cells) against the human receptor. Netupitant antagonizes the effects induced by Substance P, inhibits the maximal response of Substance P with a long-lasting action, and suppresses NK1 agonist-induced behaviors in mice and gerbils. Netupitant reduces the frequency of bladder contractions, prolongs contraction intervals, decreases basal pressure at high doses, and acts on the afferent branch of the micturition reflex. Netupitant can be used in research related to overactive bladder, chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, anxiety disorders, and depression .
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3 Cited Publications
Cat. No.: HY-W009371
CAS No.: 18265-46-8
3
3 Cited Publications
Cat. No.: HY-W009371C
CAS No.: 207671-46-3
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3
3 Cited Publications
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BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer .
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3 Cited Publications
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2
2 Cited Publications
Cat. No.: HY-N7948
CAS No.: 35997-20-7
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2
2 Cited Publications
Synonyms: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
Category:
Microorganisms Neurological Disease Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics Cancer
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1
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Polyethylenimine (branched) (MW 25000) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (MW 25000) can ensnare DNA as well as attach to cell membrane .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
