3793 Results for "

Natural

" in MedChemExpress (MCE) Product Catalog:
Products (3793)

3793 Results for "Natural" in MCE Product Catalog:

34
34 Cited Publications
Cat. No.: HY-12686
CAS No.: 253863-19-3
Pureté:  99.30%
Synonyms: FR148083; L783279; LL-Z 1640-2
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.
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33
33 Cited Publications
Cat. No.: HY-N0210
CAS No.: 59-23-4
Synonyms: D-(+)-Galactose
D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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31
31 Cited Publications
Cat. No.: HY-N0136
CAS No.: 480-18-2
Synonyms: (+)-Dihydroquercetin; (+)-Taxifolin
Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .
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30
30 Cited Publications
Cat. No.: HY-N0168
CAS No.: 520-33-2
Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .
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29
29 Cited Publications
Cat. No.: HY-N0737
CAS No.: 343-27-1
Synonyms: Telepathine hydrochloride
Harmine Hydrochloride (Telepathine Hydrochloride) is a natural DYRK inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM .
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29
29 Cited Publications
Cat. No.: HY-N0737A
CAS No.: 442-51-3
Synonyms: Telepathine
Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM .
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28
28 Cited Publications
Cat. No.: HY-N4000
CAS No.: 11024-24-1
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth . Digitonin is an natural detergent .
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28
28 Cited Publications
Cat. No.: HY-15689
CAS No.: 1204669-58-8
Pureté:  98.47%
Synonyms: INCB 024360
Domaines de recherche:  

Inflammation/Immunology Cancer

Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM . Epacadostat can effectively reduce Trp metabolism, entailing increased activation and maturation of dendritic cells, and enhanced proliferation of effector T cells and natural killer cells (NKs), as well as attenuated Tregs expansion.
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28
28 Cited Publications
Cat. No.: HY-13821
CAS No.: 134381-21-8
Pureté:  99.39%
Synonyms: BU-4061T
Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity .
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27
27 Cited Publications
Cat. No.: HY-15459
CAS No.: 183133-96-2
Pureté:  99.91%
Synonyms: XRP6258; RPR-116258A; taxoid XRP6258
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
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27
27 Cited Publications
Cat. No.: HY-P0223
CAS No.: 98849-88-8
Domaines de recherche:  

Inflammation/Immunology

FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions .
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27
27 Cited Publications
Cat. No.: HY-P0223A
Domaines de recherche:  

Others

FLAG peptide TFA is the TFA salt form of FLAG peptide (HY-P0223). FLAG peptide TFA is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide TFA maintances the natural folding of its fusing proteins. FLAG peptide TFA can be removed by enterokinase, and eluted under non-denaturing conditions .
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27
27 Cited Publications
Cat. No.: HY-103586
CAS No.: 1191237-69-0
Pureté:  99.89%
Domaines de recherche:  

Infection

GS-441524 is a potent, orally active and CNS-penetrant viral RNA-dependent RNA polymerase inhibitor. GS-441524 competes with natural nucleosides to block viral RNA transcription as an alternative substrate and RNA chain terminator. GS-441524 inhibits the replication of feline infectious peritonitis virus, African swine fever virus, and severe acute respiratory syndrome coronavirus 2. GS-441524 reduces viral RNA levels in cats. GS-441524 can be used in research related to feline infectious peritonitis, African swine fever, and coronavirus disease 2019 (COVID-19) .
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27
27 Cited Publications
Cat. No.: HY-103586A
CAS No.: 2378280-82-9
Domaines de recherche:  

Infection

GS-441524 hydrochloride is a potent, orally active and CNS-penetrant viral RNA-dependent RNA polymerase inhibitor. GS-441524 hydrochloride competes with natural nucleosides to block viral RNA transcription as an alternative substrate and RNA chain terminator. GS-441524 hydrochloride inhibits the replication of feline infectious peritonitis virus, African swine fever virus, and severe acute respiratory syndrome coronavirus 2. GS-441524 hydrochloride reduces viral RNA levels in cats. GS-441524 hydrochloride can be used in research related to feline infectious peritonitis, African swine fever, and coronavirus disease 2019 (COVID-19) .
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26
26 Cited Publications
Cat. No.: HY-18980
CAS No.: 82-08-6
Synonyms: Mallotoxin; NSC 56346; NSC 94525
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation . Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection .
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25
25 Cited Publications
Cat. No.: HY-K6002

MCE Basement Membrane Matrix is primarily composed of natural basement membrane matrix extracted from mouse tumors.This product is mainly used for studies of tumor invasion, angiogenesis and organoids culture while avoiding color interference in subsequent experiments.

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25
25 Cited Publications
Cat. No.: HY-N0288
CAS No.: 476-28-8
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription . Lycorine is also a melanoma vasculogenic inhibitor . Lycorine can be used for the study of prostate cancer and metabolic diseases .
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24
24 Cited Publications
Cat. No.: HY-N0156
CAS No.: 508-02-1
Synonyms: Oleanic acid; Caryophyllin
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
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22
22 Cited Publications
Cat. No.: HY-B0183A
CAS No.: 314041-08-2
Ellagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM .
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22
22 Cited Publications
Cat. No.: HY-B0183
CAS No.: 476-66-4
Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2, with an IC50 of 40 nM and a Ki of 20 nM.
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