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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1041 Results for "
Acid Red
" in MedChemExpress (MCE) Product Catalog:
Products (1041)
1041 Results for "Acid Red" in MCE Product Catalog:
Cat. No.: HY-D1470
CAS No.: 210832-86-3
Target:
Research Areas:
BADAN is a thiol-reactive, environment-sensitive fluorescent probe used for site-specific labeling of protein cysteine residues to detect protein topology, local polarity, protein-lipid interactions, and conformational changes. The bromoacetyl group of BADAN covalently binds to cysteine thiols, and its fluorescence originates from the intramolecular charge transfer (ICT) excited state. The emission peak position varies with the polarity of the surrounding medium: it blue-shifts to approximately 488 nm in nonpolar environments (such as the hydrophobic core of lipid bilayers) and red-shifts to approximately 496-507 nm in polar environments (such as aqueous phases), independent of enzymes, pH, or membrane potential. Ex = 380-402 nm; Em = 400-600 nm .
Cat. No.: HY-D3109
CAS No.: 148043-22-5
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pH-Ap-1 is a fluorescent probe used for ratiometric monitoring of pH fluctuations during autophagy in living cells, and it can detect intracellular pH changes in the autophagy process. For fluorescence detection of pH-Ap-1, its excitation wavelength is 475 nm, with an emission wavelength of 538 nm under alkaline conditions and 645 nm under acidic conditions. For intracellular imaging, excitation is performed at 488 nm: the emission light ranging from 500-550 nm is collected via the green channel corresponding to 538 nm, while the emission light ranging from 625-750 nm is collected via the red channel corresponding to 645 nm. pH-Ap-1 exhibits excellent photostability and chemical stability .
Cat. No.: HY-D3443
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NR-HOCl-TFMU is a HOCl-gated phosphonite fluorescent probe based on the Nebraska Red scaffold. NR-HOCl-TFMU undergoes HOCl-triggered oxidative ring-opening of the spirocyclic thioether and phosphonite hydrolysis to synchronously release the near-infrared reporter group NR666-MSA (Ex 666 nm/Em 698 nm) and the cargo TFMU (Ex 405 nm/Em 510 nm) . NR-HOCl-TFMU enables HOCl-selective fluorescence imaging and cargo release monitoring in vitro, in live cells and in vivo, and exerts gated selective cytotoxicity in HOCl-positive cells. NR-HOCl-TFMU can be used for studies related to acute myeloid leukemia .
Cat. No.: HY-DY1006
CAS No.: 25535-16-4
Solvent and Concentration: Sterile water: 1 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-DY1111
CAS No.: 1539318-40-5
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DFHBI-2T solution is a membrane-permeable, RNA aptamer-activated fluorescent probe (Ex/Em=500 nm/523 nm), with a Kd value of 1300 nM for the RNA aptamer Spinach2. DFHBI-2T solution binds to Spinach2, converting the fluorophore to a fluorescent state, stabilizing its planar structure to facilitate the radiative fluorescence decay pathway, and forming a complex with red-shifted excitation and emission peaks. DFHBI-2T solution can be used for RNA imaging in live cells. It is also applicable to research related to fragile X-associated tremor/ataxia syndrome .
Solvent and concentration: DMSO: 5 mM
Solvent and concentration: DMSO: 5 mM
Cat. No.: HY-NP0144
Synonyms: WGA (Fluorescein)
Cat. No.: HY-W088068
CAS No.: 68988-92-1
Cat. No.: HY-P71267
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RRM2; FLJ25102; Prev. C2orf48; Chromosome 2 Open Reading Frame 48; Ribonucleoside-Diphosphate Reductase Subunit M2; Uncharacterized Protein C2orf48; Ribonucleotide Reductase Small Subunit; RR2M; Ribonucleotide Reductase Small Chain; R2; Ribonucleotide Red
Species:
Human
Source:
HEK293
Cat. No.: HY-P700578
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PKLR; Pyruvate Kinase, Liver And Blood Cell; Pyruvate Kinase L/R; Pyruvate Kinase Isozymes R/L; Pyruvate Kinase, Liver And RBC; Pyruvate Kinase Isozyme R/L; Red Cell/Liver Pyruvate Kinase; Pyruvate Kinase Isoform 1; R-Type/L-Type Pyruvate Kinase; Pyruvate
Species:
Rat
Source:
P. pastoris
Cat. No.: HY-P10881
CAS No.: 2758595-29-6
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Ganipatide is a 1-31-Glucose-dependent insulinotropic polypeptide. Ganipatide is promising for research of diabetes .
Cat. No.: HY-125959R
CAS No.: 313649-08-0
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Ucf-101 (Standard) is the analytical standard of Ucf-101. This product is intended for research and analytical applications. Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect .
Cat. No.: HY-133535
CAS No.: 2093120-32-0
Synonyms: PA-JF646-NHS
Cat. No.: HY-173054
CAS No.: 3099249-36-9
FtsZ-IN-12 (Compound 16e) is the inhibitor for filamentous temperature-sensitive mutant Z (FtsZ) that promotes the polymerization of FtsZ protein, inhibits its GTPase activity, thereby interfering with bacterial cell division process. FtsZ-IN-12 exhibits boardspectrum antibacterial activity that inhibits B. subtilis ATCC9372, B. pumilus CMCC63202, S. aureus ATCC25923, E. coli BW25113 and A. baumannii ATCC19606 with MIC of 0.062-1 μg/mL. FtsZ-IN-12 inhibits the formation of bacterial biofilms and exhibits a clearing effect on mature biofilms. FtsZ-IN-12 exhibits bactericidal activity without hemolytic toxicity to mammalian red blood cells (15 mg/kg) .
Synonyms: L-α-Phosphatidylcholine (egg yolk, Type XVI-E), 99%, lyophilized powder; 1,2-Diacyl-sn-glycero-3-phosphocholine (egg yolk, Type XVI-E), 99%; egg yolk Lecithins, Type XVI-E, 99%
Cat. No.: HY-D0922
CAS No.: 1284240-77-2
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Cy3.5 is a cyanine-based red fluorescent dye (Ex/Em ≈ 560-581/600-612 nm). After covalent conjugation with proteins, Cy3.5 exhibits extraordinary fluorescence enhancement with minimal quenching even at high labeling ratios. Cy3.5 can form a FRET dye pair with Cy5.5, which maintains stable FRET efficiency in various biochemical buffers and deoxygenated systems. Cy3.5 is applicable to studies related to fluorescent labeling of antibodies/proteins, single-molecule FRET imaging of double-stranded DNA and nucleosomes, SPION functionalization, in vivo tracing, and other relevant research .
Cat. No.: HY-D0922A
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Cy3.5 acetate is a cyanine-based red fluorescent dye (Ex/Em ≈ 560-581/600-612 nm). After covalent conjugation with proteins, Cy3.5 acetate exhibits extraordinary fluorescence enhancement with minimal quenching even at high labeling ratios. Cy3.5 acetate can form a FRET dye pair with Cy5.5, which maintains stable FRET efficiency in various biochemical buffers and deoxygenated systems. Cy3.5 acetate is applicable to studies related to fluorescent labeling of antibodies/proteins, single-molecule FRET imaging of double-stranded DNA and nucleosomes, SPION functionalization, in vivo tracing, and other relevant research .
Cat. No.: HY-W718178
CAS No.: 152-84-1
Target:
Cat. No.: HY-121365
CAS No.: 71522-58-2
Forphenicinol is an immunomodulator and a derivative of the bacterial metabolite forphenicine. It increases the phagocytosis of yeast by peritoneal macrophages isolated from thioglycolate-stimulated mice. Forphenicinol (100 μg/animal) prevents cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH), as well as enhances DTH in response to the hapten oxazolone or sheep red blood cells in mice. It enhances the bactericidal activity of macrophages against P. aeruginosa in mice when administered at a dose of 0.5 mg/kg.2 Forphenicinol (15.6-1,000 μg/animal) increases survival in a mouse model of P. aeruginosa infection. It also inhibits tumor growth in S180 sarcoma and IMC carcinoma mouse xenograft models when administered at doses ranging from 0.05 to 5 mg/kg per day.
Synonyms: JF646, Tetrazine
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Thiocoumarin is a carbonic anhydrase (CA) inhibitor, with Ki values of 0.047 μM, 0.042 μM, and 0.1 μM against hCA IX, mCA XIII, and hCA I, respectively; its Ki values against hCA IV, mCA XV, hCA II, hCA VA, hCA VB, hCA VI, hCA VII, hCA XII, and hCA XIV are 4.1, 4.8, 6.2, 8.4, 7.5, 8.8, 7.3, 8.7, and 7.4 μM, respectively . As a photocage molecule, Thiocoumarin undergoes photolysis upon illumination to release the caged molecule, and it exhibits red-shifted absorption properties and rapid photolysis kinetics. Thiocoumarin can be used in cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
