10084 Results for "

Protection against convulsion

" in MedChemExpress (MCE) Product Catalog:
Products (10084)

10084 Results for "Protection against convulsion" in MCE Product Catalog:

Cat. No.: HY-N20649
CAS No.: 67068-82-0
Isorhamnetin-3-O-rhamnoside is an acetylcholinesterase (AChE) inhibitor with moderate antioxidant activity, with an IC50 of 73.96 µM against electric eel AChE. Isorhamnetin-3-O-rhamnoside significantly inhibits the proliferation of mammary adenocarcinoma cells, but exerts relatively weak inhibitory effects on liver cancer cells and lung cancer cells. Isorhamnetin-3-O-rhamnoside can be widely used in studies related to Alzheimer's disease and human mammary adenocarcinoma .
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Cat. No.: HY-N21660
CAS No.: 854629-43-9
2,5-Dihydro-5-oxo-5-furanoctanoic acid is a fatty acid found in the flower buds of Hemerocallis citrina Baroni. 2,5-Dihydro-5-oxo-5-furanoctanoic acid exhibits inhibitory activity against LPS-induced NO production in BV2 microglia, with an IC50 of 71.16 μM. 2,5-Dihydro-5-oxo-5-furanoctanoic acid can be used for the study of neuroinflammation .
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Cat. No.: HY-N21895
CAS No.: 96789-48-9
(Z)-Corallopyronin A is an isomer of Corallopyronin A (HY-N11622). Corallopyronin A is a polyketide natural product derived from myxobacteria and acts as a bacterial RNA polymerase (RNAP) inhibitor with antibacterial activity. Corallopyronin A binds to the switch region of RNA polymerase and allosterically blocks the transcription initiation process. Corallopyronin A exhibits in vitro antibacterial activity against Staphylococcus aureus, coagulase-negative staphylococci, Neisseria gonorrhoeae, and the filarial endosymbiont Wolbachia. (Z)-Corallopyronin A can be used for research related to bacterial infections .
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Cat. No.: HY-N2214
CAS No.: 329361-25-3
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple agent resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively. 7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026 mM and 0.021 mM for DPPH and 2-deoxyribose degradation assay, respectively.
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Cat. No.: HY-N2359A
CAS No.: 478-03-5
Chelerythrine hydroxide is an alkaloid, acts as a potent and selective Ca 2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine hydroxide inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM. Chelerythrine hydroxide triggers Apoptosis and Autophagy. Chelerythrine hydroxide has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine hydroxide shows antibacterial activities against Gram-positive bacteria, Staphylococcus aureus (SA), MRSA .
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Cat. No.: HY-N3364
CAS No.: 19956-53-7
Lucidone, an anti-inflammatory agent that can be isolated from the fruit of Lindera erythrocarpa Makino. Lucidone inhibits LPS-induced NO and PGE2 production in RAW 264.7 mouse macrophages. Lucidone also decreases TNF-α secretion, iNOS and COX-2 expression. Lucidone prevents NF-κB translocation and inhibits JNK and p38MAPK signals. Lucidone also has inhibitory activity against Dengue virus (DENV) (EC50=25 μM) .
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Cat. No.: HY-N7058R
CAS No.: 488-10-8
cis-Jasmone (Standard) is the analytical standard of cis-Jasmone. This product is intended for research and analytical applications. Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
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Cat. No.: HY-N7066R
CAS No.: 91296-86-5
Synonyms: A-56619 hydrochloride (Standard)
Research Areas:  

Infection

Difloxacin hydrochloride (Standard) (A-56619 hydrochloride (Standard)) is the analytical standard of Difloxacin (hydrochloride) (HY-N7066). This product is intended for research and analytical applications. Difloxacin hydrochloride (A-56619 hydrochloride) is an orally active bactericidal agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase. Difloxacin hydrochloride exhibits concentration-dependent bactericidal activity. Difloxacin hydrochloride shows strong in vitro activity against a variety of Gram-positive and Gram-negative bacteria. Difloxacin hydrochloride can be used in research related to colibacillosis and *Staphylococcus aureus* infections .
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Cat. No.: HY-N7085R
CAS No.: 487-06-9
Synonyms: 5,7-Dimethoxycoumarin (Standard); Limettin (Standard)
Citropten (Standard) is the analytical standard of Citropten. This product is intended for research and analytical applications. Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis .
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Cat. No.: HY-N7929R
CAS No.: 40242-06-6
5-Feruloylquinic acid (Standard) is the analytical standard of 5-Feruloylquinic acid (HY-N7929). This product is intended for research and analytical applications. 5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .
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Cat. No.: HY-N8036
CAS No.: 1007860-05-0
(2R,3R)-Pterosin L 3-O-β-D-glucopyranoside is an glucoside compound found in the aerial parts of Pteris multifida. (2R,3R)-Pterosin L 3-O-β-D-glucopyranoside shows cytotoxicity against cancer cells. (2R,3R)-Pterosin L 3-O-β-D-glucopyranoside can be used for the research of cancer, such as human epidermoid carcinoma .
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Cat. No.: HY-N8487R
CAS No.: 22395-22-8
7-Methoxyflavone (Standard) is the analytical standard of 7-Methoxyflavone (HY-N8487). This product is intended for research and analytical applications. 7-Methoxyflavone is a flavonoid compound that can be isolated from Zornia brasiliensis. 7-Methoxyflavone can bind to human serum albumin and is an aromatase inhibitor. 7-Methoxyflavone has peripheral analgesic and certain antitumor activities. 7-Methoxyflavone is effective against chemical pain but has no significant effect on thermal pain .
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Cat. No.: HY-N8497
CAS No.: 105350-54-7
Leoidin is an OATP1B1 and OATP1B3 inhibitor with Ki values of 0.08 and 1.84 μM, respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC50= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides .
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Cat. No.: HY-N9778
CAS No.: 886747-62-2
Phoyunbene B is a similar substance to Resveratrol (HY-16561). Phoyunbene B exhibits stronger growth inhibitory activity against human liver cancer cells HepG2 compared to Resveratrol. Phoyunbene B induces G2/M phase cell cycle arrest and apoptosis. Phoyunbene B increases Bax/Bcl-2 and activates Caspase-3. Phoyunbene B inhibits the invasion and migration of cancer cells. Phoyunbene B can be used for research on liver cancer .
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Cat. No.: HY-N9907
CAS No.: 53947-99-2
7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is an isoflavone Antibacterial agent. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is isolated from the stems of S. parviflorus. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone exhibits weak antibacterial activity against Gram-positive and Gram-negative bacterial strains. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone can be used in the research of bacterial infections .
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Cat. No.: HY-P10607
CAS No.: 610268-80-9
Target:  

EBV

Research Areas:  

Cancer

IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW is able to activate EBV-specific cytotoxic T lymphocytes (CTLs), which are able to recognize and kill EBV-infected cells expressing LMP1. IALYLQQNW plays an important role in the immune response against EBV-associated tumors and can be used in the study of Hodgkin's disease and nasopharyngeal carcinoma .
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Cat. No.: HY-P11262
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GUB021794 is a potent and highly selective glucagon-like peptide-1 receptor (GLP-1R) agonist developed using the streaMLine platform with an EC50 value of 18 pM. GUB021794 has a very weak activity against SCTR, with an EC50 value of 190 nM. GUB021794 can significantly reduce the body weight, food intake, and total fat mass of mice in a diet-induced obesity (DIO) model. GUB021794 can be used for research on obesity/diabetes .
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Cat. No.: HY-P11658
CAS No.: 620948-14-3
Synonyms: Peptoid 1
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Anticancer peptoid 1 (Peptoid 1) is a peptoid with antitumor activity. Anticancer peptoid 1 exerts cytotoxicity primarily via plasma membrane damage. Anticancer peptoid 1 exerts cytotoxicity against a broad range of cancer cell lines, including those with multidrug resistance. Anticancer peptoid 1 inhibits tumor growth in a human breast cancer xenotransplantation mouse model without noticeable acute adverse effects. Anticancer peptoid 1 can be used for the research of cancer, such as breast cancer, and prostate cancer .
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Cat. No.: HY-P11898
Target:  

Bacterial

Research Areas:  

Infection

RBWH15 is a synthetic broad-spectrum antimicrobial peptide. RBWH15 increases the permeability of bacterial outer and inner membranes, disrupts membrane integrity and induces bacterial death. RBWH15 exhibits biofilm eradication activity and can eliminate established bacterial biofilms. RBWH15 shows broad-spectrum antimicrobial activity against Gram-negative and Gram-positive ESKAPE pathogens, including multidrug-resistant strains. RBWH15 can be used in the research of multidrug-resistant bacterial infections .
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Cat. No.: HY-P12210
CAS No.: 1001644-68-3
Research Areas:  

Infection

Antimicrobial peptide BP100 is a linear undecapeptide with an amphipathic α-helical structure that exhibits antibacterial activity. Antimicrobial peptide BP100 shows in vitro antibacterial activity against a variety of plant and human pathogens. Antimicrobial peptide BP100 binds to and inserts into bacterial cell membranes through electrostatic attraction, triggering membrane permeabilization and ultimately leading to membrane disruption. Antimicrobial peptide BP100 can be used for research on bacterial infections .
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