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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
447 Results for "
ACE
" in MedChemExpress (MCE) Product Catalog:
Products (447)
447 Results for "ACE" in MCE Product Catalog:
42
42 Publications Verification
Synonyms: Frangula emodin
Category:
Polygonaceae Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Cancer
Target:
30
30 Cited Publications
Synonyms: Ursodeoxycholate; Ursodiol; UDCA
25
25 Cited Publications
Referencia número: HY-19414
No. CAS: 305335-31-3
Áreas de investigación:
MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
23
Áreas de investigación:
Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM .
21
Áreas de investigación:
Cardiovascular Disease Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Methylprednisolone (U 7532) is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .
17
17 Cited Publications
Synonyms: TXA127 ACEtate; Angiotensin (1-7) ACEtate; Ang-(1-7) ACEtate
17
17 Cited Publications
Synonyms: TXA127; Angiotensin (1-7); Ang-(1-7)
14
14 Cited Publications
Synonyms: Diminazene diACEturate
Áreas de investigación:
Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .
8
8 Cited Publications
Referencia número: HY-N2165
No. CAS: 23666-13-9
8
8 Cited Publications
5
5 Cited Publications
Referencia número: HY-P99720
No. CAS: 1373715-00-4
Synonyms: ACE-536; luspatercept–aamt
Target:
Áreas de investigación:
5
3
Áreas de investigación:
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
3
3
Áreas de investigación:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Benazepril (CGS14824A) hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril hydrochloride inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. In addition, Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria. Benazepril hydrochloride can be used in the study of hypertension, heart failure and diabetic nephropathy .
3
3
3 Cited Publications
Referencia número: HY-N0214A
No. CAS: 900498-44-4
Synonyms: Ebeiensine hydrochloride
3
Áreas de investigación:
3
3 Cited Publications
Referencia número: HY-P2222
No. CAS: 478188-26-0
Áreas de investigación:
3
3 Cited Publications
Referencia número: HY-P2222A
Áreas de investigación:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
