66 Results for "

Bitter

" in MedChemExpress (MCE) Product Catalog:
Products (66)

66 Results for "Bitter" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0917
CAS No.: 51011-05-3
Synonyms: Malonylgenistin; Genistin malonate
6''-O-Malonylgenistin (Malonylgenistin) is a glycosylated isoflavone and metabolite of Genistin (HY-N0595). 6''-O-Malonylgenistin activates hTAS2R39. 6''-O-Malonylgenistin can be used in the research of bitter taste .
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1 Cited Publications
Cat. No.: HY-W007035
CAS No.: 27493-61-4
Synonyms: Valyl-alanine
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .
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1 Cited Publications
Cat. No.: HY-Y0585
CAS No.: 611-71-2
D-(-)-Mandelic acid is an orally active alpha hydroxycarboxylic acid that can be isolated from bitter almonds and Indian chestnut trees. It has antioxidant and antibacterial properties and is expected to play an important role in the treatment of rheumatoid arthritis .
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1 Cited Publications
Cat. No.: HY-B1146
CAS No.: 3734-33-6
Synonyms: THS-839
Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors (TAS2Rs) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .
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1 Cited Publications
Cat. No.: HY-N0742
CAS No.: 1362-42-1
Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca 2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46 .
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Cat. No.: HY-100047
CAS No.: 113231-05-3
Purity:  98.80%
Target:  

Taste Receptor

Research Areas:  

Others

Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .
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Cat. No.: HY-123026
CAS No.: 992-20-1
Purity:  99.30%
Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-W010607
CAS No.: 928-96-1
Synonyms: (Z)-3-Hexen-1-ol
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is a green grassy smelling compound found in many fresh fruits and vegetables with bitter taste enhancement. cis-3-Hexen-1-ol is widely used as an added flavor in processed food to provide a fresh green quality. cis-3-Hexen-1-ol is an attractant to various insects .
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Cat. No.: HY-W004842
CAS No.: 4265-16-1
Target:  

Fungal

Research Areas:  

Others

Benzofuran-2-carboxaldehyde is a benzofuran derivative with a bitter almond odor. Benzofuran-2-carboxaldehyde exhibits high antifungal activity .
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Cat. No.: HY-111664
CAS No.: 2385-77-5
Purity:  98.72%
Synonyms: (+)-Citronellal
(R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC50 = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain .
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Cat. No.: HY-W009141
CAS No.: 542-44-9
Synonyms: Glyceryl palmitate
Category:  

Plants

1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells .
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Cat. No.: HY-N8290
CAS No.: 65725-11-3
Synonyms: Lactucopicrin
Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC50 of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone .
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Cat. No.: HY-124257
CAS No.: 1117-61-9
Purity:  99.78%
Synonyms: D-Citronellol; (R)-(+)-β-Citronellol
(R)-Citronellol (D-Citronellol) is an alcoholic monoterpene found in geranium essential oil. (R)-Citronellol inhibits degranulation of mast cells and does not affect caffeine bitterness perception. (R)-Citronellol can be used in decorative cosmetics, toiletries as well as in non-cosmetic products .
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Cat. No.: HY-129847
CAS No.: 80863-62-3
Purity:  99.79%
Research Areas:  

Others

Alitame is a nonnutritive high-intensity sweetener, 2000 times sweeter than sucrose with no bitter or metallic aftertaste. Alitame is composed of L-aspartic acid, D-alanine, and a C-terminal amide moiety .
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Cat. No.: HY-P4648
CAS No.: 59005-82-2
Synonyms: Trp-Trp-Trp
Target:  

Bacterial

Research Areas:  

Infection

H-Trp-Trp-Trp-OH (Trp-Trp-Trp) is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity. H-Trp-Trp-Trp-OH is a human bitter taste receptor hTAS2R14 agonist .
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Cat. No.: HY-153265
CAS No.: 2883007-69-8
Purity:  99.91%
Target:  

Taste Receptor

Research Areas:  

Inflammation/Immunology

TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 agonist with an EC50 value of 72 nM. TAS2R14 agonist-2 reveals marked selectivity over a panel of 24 non-bitter taste human G protein-coupled receptors. TAS2R14 agonist-2 can be used for the studies of asthma or chronic obstructive pulmonary disease .
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Cat. No.: HY-N6992
CAS No.: 64432-06-0
Dulcoside A is a glycoside that can be isolated from Stevia rebaudiana that elicits sweet and bitter taste through activation of TAS1R. Dulcoside A also exhibits anti-inflammatory activity .
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Cat. No.: HY-N8210
CAS No.: 446-71-9
Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo .
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Cat. No.: HY-121376
CAS No.: 29883-16-7
Purity:  99.59%
Neoamygdalin is a compound identified in the different processed bitter almonds. Neoamygdalin has the potential for the research of cough and asthma .
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Cat. No.: HY-119309
CAS No.: 126-14-7
Purity:  ≥98.0%
Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .
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