106 Results for "

IGFBP

" in MedChemExpress (MCE) Product Catalog:
Products (106)

106 Results for "IGFBP" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-110135
CAS No.: 374620-70-9
Pureté:  98.88%
Target:  

IGF-1R

Domaines de recherche:  

Neurological Disease Inflammation/Immunology

NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation .
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3
3 Cited Publications
Cat. No.: HY-110135A
Pureté:  99.42%
Target:  

IGF-1R

Domaines de recherche:  

Neurological Disease

NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .
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2
2 Cited Publications
Cat. No.: HY-N1990
CAS No.: 94987-08-3
Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation .
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2
2 Cited Publications
Cat. No.: HY-P7368
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIGF-BP-2, His; IBP-2; IGFBP-2; BP2
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2
2 Cited Publications
Cat. No.: HY-P72153
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; IGFBP-8; IGFBP8; NOV2
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2
2 Cited Publications
Cat. No.: HY-P7021
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuIGF-BP5; IBP-5
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2
2 Cited Publications
Cat. No.: HY-P72154
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; Ctgf; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; MGC102839; NOV 2; NOV2
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2
2 Cited Publications
Cat. No.: HY-P7842
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuCCN family member 1/Cyr61, Fc; Protein CYR61; CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10 ; GIG1; CYR61; CCN1; IGFBP10;
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1
1 Cited Publications
Cat. No.: HY-W074890
CAS No.: 2441-41-0
Synonyms: N-palmitoyl glycine
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .
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1
1 Cited Publications
Cat. No.: HY-N3316
CAS No.: 67884-12-2
Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway .Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels
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1
1 Cited Publications
Cat. No.: HY-P72378
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-Like Growth Factor-Binding Protein 5; IBP-5; IGF-Binding Protein 5; IGFBP-5; IGFBP5; IBP5
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1
1 Cited Publications
Cat. No.: HY-P70726
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF
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1
1 Cited Publications
Cat. No.: HY-P70408
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuInsulin-like growth factor-binding protein 5/IGFBP5, His; BP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;
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1
1 Cited Publications
Cat. No.: HY-P704010
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: sCcn1; Cyr61; IGFBP10; CCN family member 1; 3CH61; Cellular communication network factor 1; Cysteine-rich angiogenic IGFBP-10; Protein CYR61; inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10
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1
1 Cited Publications
Cat. No.: HY-P78104
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839
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1
1 Cited Publications
Cat. No.: HY-P70602
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CTGF; IGFBP8
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1
1 Cited Publications
Cat. No.: HY-P70106
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuConnective tissue growth factor/CTGF; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8
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Cat. No.: HY-RS06626
Domaines de recherche:  

Others

IGFBP3 Human Pre-designed siRNA Set A contains three designed siRNAs for IGFBP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991042

Target:  

IGF-1R

Domaines de recherche:  

Cancer

Anti-IGFBP2 Antibody (M14) is an human anti-IGFBP2 monoclonal inhibitory antibody, which binds IGFBP2 with high affinity and blocks its binding with IGF1. Anti-IGFBP2 Antibody (M14) inhibits human endothelial cell recruitment, thus blocks the tumor progression of human metastatic cancer .
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Cat. No.: HY-W074890R
CAS No.: 2441-41-0
Synonyms: N-palmitoyl glycine (Standard)
Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
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