238 Results for "

IL-4

" in MedChemExpress (MCE) Product Catalog:
Products (238)

238 Results for "IL-4" in MCE Product Catalog:

63
63 Publications Verification
Cat. No.: HY-P70445
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
Species:  
Source:  
loading...
    loading...
54
54 Cited Publications
Cat. No.: HY-P7080
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Species:  
Source:  
CHO
loading...
    loading...
26
26 Cited Publications
Cat. No.: HY-P70644
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; IGG1 induction factor; Lymphocyte stimulatory factor 1; IL-4; BSF-1
Species:  
Source:  
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-B0539
CAS No.: 100643-71-8
Synonyms: Sch34117
Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria [4] .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-P70653
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; IL-4; IL4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; Lymphocyte stimulatory factor 1
Species:  
Source:  
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-P9926
CAS No.: 1190264-60-8
Synonyms: REGN-668; SAR-231893

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P70750
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
Species:  
Source:  
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P701093
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Species:  
Source:  
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-113402
CAS No.: 636-58-8
Purity:  95.20%
Synonyms: γ-Glu-Cys
Gamma-glutamylcysteine (γ-Glu-Cys) is an orally active, blood-brain barrier permeable dipeptide . Gamma-glutamylcysteine activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways; it inhibits NF-κB, JAK1/STAT1/3, MAPKs, cadmium-induced p38 MAPK, JNK, and PI3K/Akt signaling pathways. Gamma-glutamylcysteine regulates macrophage polarization, modulates the trafficking of CD36 and GLUT4, induces glutathione synthesis, improves metabolic dysfunction, reduces lipid deposition, ameliorates glucose homeostasis, inhibits apoptosis (Apoptosis), stabilizes mitochondria, suppresses lipid peroxidation, iron accumulation and ferroptosis (Ferroptosis), reduces ds-HMGB1 levels, reverses mechanical hyperalgesia, and alleviates hepatic lipid droplet formation. Gamma-glutamylcysteine is applicable to research related to inflammatory bowel disease, type 2 diabetes, cadmium-induced neurotoxicity, Alzheimer's disease, cerebral ischemia/reperfusion injury, neuropathy, and alcoholic liver disease [4] .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-113402A
CAS No.: 283159-88-6
Purity:  95.20%
Synonyms: γ-Glu-Cys TFA
Gamma-glutamylcysteine TFA (γ-Glu-Cys TFA) is an orally active, blood-brain barrier permeable dipeptide . Gamma-glutamylcysteine TFA activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways; it inhibits NF-κB, JAK1/STAT1/3, MAPKs, cadmium-induced p38 MAPK, JNK, and PI3K/Akt signaling pathways. Gamma-glutamylcysteine TFA regulates macrophage polarization, modulates the trafficking of CD36 and GLUT4, induces glutathione synthesis, improves metabolic dysfunction, reduces lipid deposition, ameliorates glucose homeostasis, inhibits apoptosis (Apoptosis), stabilizes mitochondria, suppresses lipid peroxidation, iron accumulation and ferroptosis (Ferroptosis), reduces ds-HMGB1 levels, reverses mechanical hyperalgesia, and alleviates hepatic lipid droplet formation. Gamma-glutamylcysteine TFA is applicable to research related to inflammatory bowel disease, type 2 diabetes, cadmium-induced neurotoxicity, Alzheimer's disease, cerebral ischemia/reperfusion injury, neuropathy, and alcoholic liver disease [4] .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-139092
CAS No.: 1332184-63-0
Purity:  98.04%
Target:  

Interleukin Related

Research Areas:  

Infection Cancer

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P78549
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
Species:  
Source:  
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P7042
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Species:  
Source:  
CHO
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N4087
CAS No.: 66663-90-9
Platycodin D2 is an orally active triterpenoid saponin found in Platycodon grandiflorum. Platycodin D2 induces mitophagy in cancer cells through NIX, thereby activating the P21/CyclinA2 pathway and promoting cell senescence. Platycodin D2 induces mitochondrial dysfunction, enhances autophagy, inhibits hepatocellular carcinoma cell proliferation, and exhibits anti-tumor activity against multiple cancer cell types. Platycodin D2 promotes mRNA expression of T-bet, GATA-3, Th1 cytokines IL-2 and IFN-γ, and Th2 cytokines IL-4 and IL-10, enhances splenocyte proliferation, and acts as a vaccine adjuvant with low rabbit red blood cell hemolytic activity. Platycodin D2 induces mitochondrial ROS production, incomplete autophagy, and ferroptosis to inhibit breast cancer cell proliferation. Platycodin D2 can be used for the research of cancer, inflammation and immunology .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P700130AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P700248AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rPoIL-4; BSF-1; IL4
Species:  
Pig
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1921
CAS No.: 32685-93-1
Edpetiline is an anti-inflammatory agent. Edpetiline inhibits the phosphorylation of IκB, nuclear transcription/translocation of NF-κB p65, as well as the phosphorylation of p38 MAPK and ERK MAPK. Edpetiline reduces intracellular ROS levels, inhibits the expression of TNF-α, IL-6, iNOS, COX-2, and promotes the expression of IL-4. Edpetiline is applicable to the research of diseases associated with inflammation and oxidative stress .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-154629
CAS No.: 8008-74-0
Purity:  ≥98.0%
Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities [4] .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-110261
CAS No.: 916232-21-8
Purity:  99.09%
Target:  

IKK E1/E2/E3 Enzyme NF-κB

Research Areas:  

Inflammation/Immunology

GS143 is a selec­tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCF βTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB acti­va­tion and tran­scrip­tion of tar­get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P990121

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse IL-4 Antibody (11B11) is an anti-mouse IL-4 IgG1 monoclonal antibody. Anti-Mouse IL-4 Antibody (11B11) can inhibit Th2 cell differentiation by blocking the IL-4 signaling pathway. Anti-Mouse IL-4 Antibody (11B11) can significantly reduce fibrosis combined with anti-IL13 mAb. Anti-Mouse IL-4 Antibody (11B11) can be used for researches on cancer and inflammation conditions such as colorectal cancer and prostatitis .
loading...
    loading...