759 Results for "

Natural compounds

" in MedChemExpress (MCE) Product Catalog:
Products (759)

759 Results for "Natural compounds" in MCE Product Catalog:

138
Curcumin
Curcumin
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138 Publications Verification
Cat. No.: HY-N0005
CAS No.: 458-37-7
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
Category:  

Anti-aging Zingiberaceae Extract Plants Food Research Sunscreen Pigments Phenols Polyphenols Cosmetic Research Curcuma longa Disease Research Fields Cancer

Target:  

Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis Apoptosis

Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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47
Cryptotanshinone
Cryptotanshinone
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47 Cited Publications
Cat. No.: HY-N0174
CAS No.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Category:  

Quinones Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones Cancer Labiatae Extract

Target:  

STAT Autophagy

Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
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34
5Z-7-Oxozeaenol
5Z-7-Oxozeaenol
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34 Cited Publications
Cat. No.: HY-12686
CAS No.: 253863-19-3
Purity:  99.30%
Synonyms: FR148083; L783279; LL-Z 1640-2
Category:  

Natural Products Microorganisms Monophenols Phenols Disease Research Fields Inflammation/Immunology

Target:  

MAP3K VEGFR Antibiotic

5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.
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31
Taxifolin
Taxifolin
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31 Cited Publications
Cat. No.: HY-N0136
CAS No.: 480-18-2
Synonyms: (+)-Dihydroquercetin; (+)-Taxifolin
Category:  

Flavanonols Flavonoids Anti-aging Phenols Polyphenols Plants Other Families Extract Disease Research Fields Inflammation/Immunology

Target:  

TNF Receptor Free Radical Scavengers Autophagy Tyrosinase

Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .
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24
Oleanolic acid
Oleanolic acid
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24 Cited Publications
Cat. No.: HY-N0156
CAS No.: 508-02-1
Synonyms: Oleanic acid; Caryophyllin
Category:  

Triterpenes Anti-aging Terpenoids Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer

Target:  

MAP3K Autophagy Endogenous Metabolite HIV Phosphatase Influenza Virus

Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
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21
Ursolic acid
Ursolic acid
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21 Cited Publications
Cat. No.: HY-N0140
CAS No.: 77-52-1
Synonyms: Prunol; Urson; Malol
Category:  

Triterpenes Terpenoids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Endogenous metabolite Disease Research Fields Rhamnaceae Extract Cancer

Target:  

Autophagy Endogenous Metabolite

Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
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19
Gallic acid
Gallic acid
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19 Cited Publications
Cat. No.: HY-N0523
CAS No.: 149-91-7
Synonyms: 3,4,5-Trihydroxybenzoic acid
Category:  

Anti-aging Metabolic Disease Plants Other Families Extract Endogenous metabolite Microorganisms Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Cancer

Target:  

Free Radical Scavengers COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite

Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
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19
Gallic acid hydrate
Gallic acid hydrate
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19 Cited Publications
Cat. No.: HY-N0523A
CAS No.: 5995-86-8
Synonyms: 3,4,5-Trihydroxybenzoic acid hydrate
Category:  

Phenols Polyphenols Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer

Target:  

Free Radical Scavengers COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite

Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
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17
Ginkgolic acid
Ginkgolic acid
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17 Cited Publications
Cat. No.: HY-N0077
CAS No.: 22910-60-7
Synonyms: Ginkgolic acid I
Category:  

Plants Monophenols Ginkgoaceae Extract Simple Phenylpropanols Ketones, Aldehydes, Acids Phenols Ginkgo biloba L. Phenylpropanoids Disease Research Fields Cancer

Target:  

E1/E2/E3 Enzyme

Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay.
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15
Dihydrotanshinone I
Dihydrotanshinone I
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15 Cited Publications
Cat. No.: HY-N0360
CAS No.: 87205-99-0
Category:  

Cardiovascular Disease Quinones Samanea saman (Jacq.) Merr. Plants Phenanthrenequinones Disease Research Fields Labiatae Extract

Target:  

SARS-CoV

Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.
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14
Scutellarein
Scutellarein
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14 Cited Publications
Cat. No.: HY-N0752
CAS No.: 529-53-3
Synonyms: 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone
Category:  

Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Cancer Labiatae Extract

Target:  

Free Radical Scavengers Src Autophagy SARS-CoV

Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
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11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Caesalpinia sappan L. Other Diseases Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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10
Bavachinin
Bavachinin
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10 Cited Publications
Cat. No.: HY-N0234
CAS No.: 19879-30-2
Synonyms: 7-O-Methylbavachin; Bavachinin A
Category:  

Flavonoids Monophenols Flavonones Phenols Leguminosae Extract Psoralea corylifolia L. Plants Disease Research Fields Inflammation/Immunology

Target:  

Amyloid-β PPAR HIF/HIF Prolyl-Hydroxylase

Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity. .
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7
Betaine chloride
Betaine chloride
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7 Cited Publications
Cat. No.: HY-N0739
CAS No.: 590-46-5
Category:  

Ketones, Aldehydes, Acids Other Diseases Chenopodiaceae Extract Beta vulgaris Linn. Plants Disease Research Fields

Target:  

Endogenous Metabolite

Betaine chloride is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns.
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7
Daucosterol
Daucosterol
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7 Cited Publications
Cat. No.: HY-N0410
CAS No.: 474-58-8
Synonyms: Eleutheroside A; β-Sitosterol β-D-glucoside
Category:  

Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Disease Research Fields Cancer Araliaceae Extract Steroids

Target:  

Apoptosis Reactive Oxygen Species (ROS) Autophagy

Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
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7
Betaine
Betaine
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7 Cited Publications
Cat. No.: HY-B0710
CAS No.: 107-43-7
Synonyms: Trimethylglycine; carboxy-N,N,N-trimethylmethanaminium
Category:  

Natural Products Microorganisms Animals Disease markers Metabolic Disease Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite

Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns [1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity .
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6
Pulchinenoside C
Pulchinenoside C
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6 Cited Publications
Cat. No.: HY-N0205
CAS No.: 129741-57-7
Synonyms: Anemoside B4
Category:  

Triterpenes Terpenoids Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer Ranunculaceae Extract

Target:  

Others

Pulchinenoside C (Anemoside B4) is a natural compound of the herbaceous peony saponin B4, which has many biological effects, such as antitumor, neuroprotective, and anti-angiogenic activities.
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6
Salvigenin
Salvigenin
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6 Cited Publications
Cat. No.: HY-N1318
CAS No.: 19103-54-9
Synonyms: Psathyrotin
Category:  

Flavonoids Monophenols Neurological Disease Flavones Phenols Plants Other Families Extract Disease Research Fields Inflammation/Immunology

Target:  

Autophagy Apoptosis ROS Kinase

Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis .
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5
Neochlorogenic acid
Neochlorogenic acid
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5 Cited Publications
Cat. No.: HY-N0722
CAS No.: 906-33-2
Synonyms: trans-5-O-Caffeoylquinic acid
Category:  

Lonicera japonica Thunb. Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants Caprifoliaceae Extract Disease Research Fields Cancer

Target:  

NF-κB Interleukin Related TNF Receptor COX

Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF-α and IL-1β. Neochlorogenic acid suppresses iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation.
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5
Cinchonine
Cinchonine
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5 Cited Publications
Cat. No.: HY-Y0152
CAS No.: 118-10-5
Synonyms: (8R,9S)-Cinchonine; LA40221
Category:  

Alkaloids Piperidine Alkaloids Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields Cancer Rubiaceae Extract

Target:  

Apoptosis Parasite Autophagy Caspase Calcium Channel

Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells .
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