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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
PAS
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "PAS" in MCE Product Catalog:
13
13 Publications Verification
Target:
Research Areas:
PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo .
9
9 Cited Publications
Cat. No.: HY-P80704
Synonyms: HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma
4
4 Cited Publications
Cat. No.: HY-P74888
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HIF1A; Basic-Helix-Loop-Helix-PAS Protein MOP1; Hypoxia Inducible Factor 1 Subunit Alpha; HIF-1-Alpha; BHLHe78; Hypoxia Inducible Factor 1 Alpha Subunit; PASD8; Hypoxia-Inducible Factor1alpha; MOP1; Member Of PAS Superfamily 1; Class E Basic Helix-Loop-Helix Protein 78; ARNT Interacting Protein; Hypoxia-Inducible Factor 1-Alpha; ARNT-Interacting Protein; PAS Domain-Containing Protein 8; HIF1-ALPHA; Member Of PAS Protein 1; HIF1-Alpha; HIF-1alpha; BHLHE78; HIF1; HIF-1A; Hypoxia Inducible Factor 1, Alpha Subunit (Basic Helix-Loop-Helix Transcription Factor)
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P81793
Synonyms: CD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36
2
2 Cited Publications
Cat. No.: HY-P70004
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD36; Leukocyte Differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin Receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) Transcript; GP3B; Scavenger Receptor Class B, Member 3; F
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-K0604
MCE Periodic Acid-Schiff (PAS) Staining Kit is developed based on the classical Periodic Acid–Schiff (PAS) reaction principle and is suitable for the detection of glycogen and polysaccharide-containing substances in paraffin-embedded or frozen tissue sections.
1
1 Cited Publications
Cat. No.: HY-P72895
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD36; Leukocyte Differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin Receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) Transcript; GP3B; Scavenger Receptor Class B, Member 3; F
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74303
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CD36; Leukocyte Differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin Receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) Transcript; GP3B; Scavenger Receptor Class B, Member 3; F
Species:
Rat
Source:
HEK293
Cat. No.: HY-19621
CAS No.: 62054-67-5
Target:
Research Areas:
THS-044 is a modulator of the formation of the HIF2α/ARNT heterodimer. THS-044 binding stabilizes the HIF2α PAS-B folded state (KD = 2 μM), for regulating HIF2 activity in endogenous and pathological settings, and does not bind to HIF1α or ARNT PAS-B. THS-044 can be used for the study of diseases related to hypoxia .
Target:
Research Areas:
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM .
Target:
Research Areas:
KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β .
Target:
Research Areas:
M1001 is a weak hypoxia-inducible factor-2α (HIF-2α) agonist. M1001 can bind to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 can be used in chronic kidney disease research .
Cat. No.: HY-P10426
CAS No.: 1446322-73-1
Target:
Research Areas:
Cat. No.: HY-P10221A
Target:
Research Areas:
Cat. No.: HY-P10222
Target:
Research Areas:
Cat. No.: HY-W012248
CAS No.: 349-58-6
KG-655 is a ligand that specifically binds to the ARNT PAS-B domain. KG-655 binds to the internal cavity of ARNT PAS-B to restrict its variable folded conformation, disrupts the interaction between ARNT PAS-B and the transcriptional coactivator TACC3, and promotes the homodimerization of ARNT PAS-B. KG-655 is widely applicable to cancer-related research .
Cat. No.: HY-P10223
Target:
Research Areas:
Cat. No.: HY-RS22934
Target:
Research Areas:
Cd36 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd36 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N16484
CAS No.: 55727-46-3
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
