189 Results for "

Phosphocholine

" in MedChemExpress (MCE) Product Catalog:
Products (189)

189 Results for "Phosphocholine" in MCE Product Catalog:

15
15 Publications Verification
Cat. No.: HY-13685
CAS No.: 58066-85-6
Purity:  99.92%
Synonyms: HePC; Hexadecyl Phosphocholine
Target:  

Akt HIV Parasite

Research Areas:  

Infection Cancer

Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .
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12
12 Cited Publications
Cat. No.: HY-113424A
CAS No.: 4235-95-4
Purity:  98.11%
Synonyms: DOPC
1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
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12
12 Cited Publications
Cat. No.: HY-B2233B
CAS No.: 3616-04-4
Synonyms: Phosphocholine
Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties .
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12
12 Cited Publications
Cat. No.: HY-B2233
CAS No.: 107-73-3
Synonyms: Phosphocholine chloride
Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties .
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3
3 Cited Publications
Cat. No.: HY-17552
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate; Alpha-GPC; L-α-GPC
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .
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3
3 Cited Publications
Cat. No.: HY-107737
CAS No.: 18194-25-7
Purity:  ≥98.0%
Synonyms: 1,2-Dilauroyl-sn-glycero-3-Phosphocholine
1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells .
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2
2 Cited Publications
Cat. No.: HY-125783
CAS No.: 17364-16-8
Purity:  99.92%
Synonyms: 16:0 Lyso PC
1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .
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2
2 Cited Publications
Cat. No.: HY-109541
CAS No.: 18194-24-6
Purity:  ≥98.0%
Synonyms: DMPC; 1,2-Dimyristoyl-sn-glycero-3-Phosphocholine; Dimyristoyl phosphatidylcholine
Colfosceril miristate (DMPC) is a synthetic phospholipid. Colfosceril miristate has antiproliferative effects on various tumors. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
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1
1 Cited Publications
Cat. No.: HY-125771
CAS No.: 19420-57-6
Purity:  99.53%
Synonyms: 18:0 Lyso-PC; LPC(18:0)
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .
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1
1 Cited Publications
Cat. No.: HY-108431
CAS No.: 203192-01-2
Purity:  99.72%
Target:  

Apoptosis

Research Areas:  

Cancer

MN58b is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. MN58b reduces cell growth through the induction of apoptosis, and also has antitumoral activity .
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Cat. No.: HY-113010
CAS No.: 108341-80-6
Purity:  ≥99.0%
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).
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Cat. No.: HY-W140439
CAS No.: 19420-56-5
Synonyms: 18:1 Lyso PC
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation .
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Cat. No.: HY-W127499
CAS No.: 51779-95-4
Synonyms: DEPC; L-Dierucoyl lecithin; Dierucoyllecithin
1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity .
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Cat. No.: HY-W013063
CAS No.: 998-06-1
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research .
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Cat. No.: HY-126356
CAS No.: 35418-59-8
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases .
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Cat. No.: HY-131640
CAS No.: 3436-44-0
Purity:  ≥98.0%
Synonyms: 1,2-Didecanoyl-sn-glycero-3-Phosphocholine
Target:  

Liposome

Research Areas:  

Others

1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine that can be introduced into single-chain mean field theory as a coarse-grained model of saturated phospholipids. The 1,2-Didecanoyl PC model can be used to estimate the free energy of compressive or tensile bilayers in stacks or multilayers and gives a reasonable estimate of the free energy .
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Cat. No.: HY-W040255
CAS No.: 89947-79-5
Synonyms: PGPC
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is an oxidized phospholipid. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine reduces the viability of HUVECs, increases the levels of ferrous ions and lipid peroxidation, promotes the production of superoxide anions, and decreases the levels of glutathione and GPX4 in cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine upregulates the mRNA and protein levels of FABP3 in HUVECs, impairs mitochondrial membrane potential, and induces ferroptosis-related changes as well as mitochondrial dysfunction and damage. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine activates caspase-11 and promotes the continuous release of IL-1β from macrophages and dendritic cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine inhibits the proliferation of aortic smooth muscle cells and induces apoptosis in these cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is applicable to relevant research on atherosclerosis .
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Cat. No.: HY-142989
CAS No.: 99296-81-8
Purity:  97.3%
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .
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Cat. No.: HY-W127457
CAS No.: 34506-67-7
1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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Cat. No.: HY-146794S
CAS No.: 2097561-16-3
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine-d7 is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine.
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