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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
caffeine
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "caffeine" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W016498
CAS No.: 611-59-6
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(E)-8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM by a pathway that is independent of its actions on the A2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research .
Synonyms: D-Citronellol; (R)-(+)-β-Citronellol
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Geraniaceae Extract Other Monoterpenes Terpenoids Pelargonium hortorum Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-D2264
CAS No.: 1632296-13-9
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Caffeine Orange (Compound 1) is a fluorescent probe for caffeine detection. Caffeine Orange is a BODIPY backbone-based probe that exhibits a turn-on fluorescence response upon binding to caffeine. The detection mechanism of Caffeine Orange relies on its binding with caffeine in aqueous media, which triggers an increase in fluorescence intensity; under irradiation with a 532 nm light source, the presence of caffeine produces orange fluorescence, with an excitation wavelength of 530 nm and an emission wavelength centered at approximately 620 nm .
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-W008449
CAS No.: 6136-37-4
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Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-W178327
CAS No.: 4921-49-7
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8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine .
Cat. No.: HY-W016498S1
CAS No.: 1173018-79-5
Synonyms: 5-Acetylamino-6-amino-3-methyluracil
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AAMU (5-Acetylamino-6-amino-3-methyluracil) is the main metabolite of caffeine in the human body .
Cat. No.: HY-W016498S
CAS No.: 117490-41-2
Cat. No.: HY-W016498R
CAS No.: 611-59-6
Cat. No.: HY-W017389R
CAS No.: 69-89-6
Cat. No.: HY-141564
CAS No.: 2837939-81-6
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RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke .
Cat. No.: HY-W008449S
Cat. No.: HY-P11633
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Cat. No.: HY-103164A
CAS No.: 148589-13-3
Synonyms: CSC
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8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity .
Cat. No.: HY-W016415
CAS No.: 612-37-3
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Cat. No.: HY-119581
CAS No.: 123363-40-6
Synonyms: 9-Methyl-7-bromoeudistomin D
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MBED (9-Methyl-7-bromoeudistomin D) is a RyR agonist. MBED is a high-affinity caffeine-like probe, helps identify the caffeine-binding site in RyRs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
