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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
543 Results for "
colony
" in MedChemExpress (MCE) Product Catalog:
Products (543)
543 Results for "colony" in MCE Product Catalog:
171
171 Publications Verification
Cat. No.: HY-16749A
CAS No.: 2040295-03-0
Synonyms: PLX-3397 hydrochloride
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity .
171
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity. Pexidartinib has limited permeability to the blood-brain barrier, primarily through ABCB1 .
148
148 Cited Publications
Cat. No.: HY-P7085
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Mouse
Source:
E. coli
45
45 Cited Publications
Cat. No.: HY-P7361
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage colony Stimulating Factor; GM-CSF; Granulocyte Macrophage-colony Stimulating Factor; colony Stimulating Factor 2 (Granulocyte-Macrophage); Colo
Species:
Mouse
Source:
E. coli
23
23 Cited Publications
Cat. No.: HY-P7050
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Human
Source:
E. coli
13
13 Cited Publications
Target:
Research Areas:
GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling .
12
12 Cited Publications
Cat. No.: HY-P7247
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Rat
Source:
CHO
10
10 Cited Publications
Cat. No.: HY-P7016A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage colony Stimulating Factor; GM-CSF; Granulocyte Macrophage-colony Stimulating Factor; colony Stimulating Factor 2 (Granulocyte-Macrophage); Colo
Species:
Human
Source:
E. coli
10
10 Cited Publications
Cat. No.: HY-P7085A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Mouse
Source:
CHO
10
10 Cited Publications
Cat. No.: HY-116282C
CAS No.: 9011-18-1
Synonyms: DSS (MW 35000-45000); DXS (MW 35000-45000)
Target:
Research Areas:
Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a polymer of dehydrated glucose with a molecular weight of approximately 35000-45000. DSS with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a potent inducer of colitis. Dextran sulfate sodium salt (DSS) (MW 35000-45000) can be used to induce model acute colitis, chronic colitis, and colitis-related colon cancer. Dextran sulfate sodium salt (DSS) (MW 35000-45000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium .
10
10 Cited Publications
Target:
Research Areas:
LDC1267 is a AXL/TAM/FLT3 inhibitor with IC50 values of 42 nM, 130 nM, and 63 nM against AXL, MERTK, and TYRO3, respectively. LDC1267 blocks GAS6-induced AXL phosphorylation and the downstream AKT/ERK1/2 signaling pathway. LDC1267 inhibits cancer cell proliferation, colony formation, and glioblastoma cell invasion, without causing obvious impairment of cytotoxic autophagic flux. LDC1267 exerts a synergistic effect when used in combination with Imatinib (HY-15463) in chronic myeloid leukemia models. LDC1267 can be widely applied in studies related to glioblastoma and chronic myeloid leukemia .
9
9 Cited Publications
Cat. No.: HY-P7050A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Human
Source:
CHO
7
7 Cited Publications
Cat. No.: HY-P70553
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Mouse
Source:
HEK293
6
6 Cited Publications
Cat. No.: HY-P70353
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NAMPT; Pre-B-Cell colony-Enhancing Factor 1; Prev. PBEF1; Pre-B-Cell colony Enhancing Factor 1; Visfatin; 1110035O14Rik; PBEF; Nampt; NAmPRTase; VF; Nicotinamide Phosphoribosyltransferase; Pre-B Cell-Enhancing Factor
Species:
Human
Source:
E. coli
5
5
5 Cited Publications
Cat. No.: HY-P70263A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage colony Stimulating Factor 1; colony Stimulating Factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage colony-Stimulating Factor; PG-M-CSF; Macrophage colony-Stimulating Factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Mouse
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P7361A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage colony Stimulating Factor; GM-CSF; Granulocyte Macrophage-colony Stimulating Factor; colony Stimulating Factor 2 (Granulocyte-Macrophage); Colo
Species:
Mouse
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P701314
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NAMPT; Pre-B-Cell colony-Enhancing Factor 1; Prev. PBEF1; Pre-B-Cell colony Enhancing Factor 1; Visfatin; 1110035O14Rik; PBEF; Nampt; NAmPRTase; VF; Nicotinamide Phosphoribosyltransferase; Pre-B Cell-Enhancing Factor
Species:
Mouse
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P70576
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL3; colony-Stimulating Factor, Multiple; Interleukin 3; P-Cell Stimulating Factor; IL-3; P-Cell-Stimulating Factor; Hematopoietic Growth Factor; Mast-Cell Growth Factor; MCGF; Mast Cell Growth Factor; Multipotential colony-Stimulating Factor; MGC79398; I
Species:
Human
Source:
E. coli
4
Bimiralisib (PQR309) is an orally active, blood-brain barrier-penetrant PI3K/mTOR inhibitor with in vitro antiproliferative activity and in vivo antitumor activity. Bimiralisib induces G1 cell cycle arrest, apoptosis and cell death in cancer cells, while inhibiting cancer cell proliferation, migration, invasion, colony formation and spheroid generation. Bimiralisib upregulates the expression of E2F4. The combination of Bimiralisib with venetoclax enhances therapeutic efficacy in acute myeloid leukemia models. Bimiralisib can be used in cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
