171 Results for "

complement protein

" in MedChemExpress (MCE) Product Catalog:
Products (171)

171 Results for "complement protein" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-P7863
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding protein Li 62p; C3a; Acylation-Stimulating protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P7862
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding protein Li 62p; C3a; Acylation-Stimulating protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing protein 1; AHUS5; complement Component C3a; ASP; complement Component C3b
Species:  
Human
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P7695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P1345A
Target:  

Complement System

Research Areas:  

Neurological Disease Endocrinology

TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca 2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions .
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2
2 Cited Publications
Cat. No.: HY-P70485
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading Factor; Serum-Spreading Factor; complement S-protein; Somatomedin B; S-protein; V75; Vitronectin (Serum Spreading Factor, Somatomedin B, complement S-protein); Epibolin; VNT
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-A0183
CAS No.: 1446756-47-3
Synonyms: Phospholipids, phosphatidylserines; Serine glycerophosphatides
Category:  

Animals

Target:  

Akt TGF-β Receptor

Phosphatidylserine (Phospholipids) is a well-conserved anti-inflammatory and immunosuppressive signal. Phosphatidylserine is involved in membrane translocation and the activation of protein kinase C, participating in Akt signaling through its interaction with PIP3. The local exposure of Phosphatidylserine can interact with complement and other proteins, promoting microglial phagocytosis during critical periods of synaptic refinement. Phosphatidylserine can promote blood coagulation in the extracellular environment and acts as a "eat me" signal to clear out apoptotic cells. Phosphatidylserine can suppress inflammation in tissues by inducing TGF-β secretion and inhibiting immune responses .
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1
1 Cited Publications
Cat. No.: HY-P99905
CAS No.: 2375661-82-6
Synonyms: IBI302

Target:  

VEGFR

Efdamrofusp alfa is a bispecific fusion protein. Efdamrofusp alfa is capable of neutralizing both VEGF isoforms and C3b/C4b. Efdamrofusp alfa can be used for the research of neovascular age-related macular degeneration (nAMD) and other complement-related ocular conditions .
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1
1 Cited Publications
Cat. No.: HY-P74375
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C2; complement Component 2; complement C2; complement protein; C3/C5 Convertase; ARMD14; complement Component C2; CO2
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P75464
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QB; complement Subcomponent C1q Chain B; complement C1q B Chain; complement C1q Chain B; complement Component 1, Q Subcomponent, Beta Polypeptide; complement Component C1q, B Chain; complement Component 1, Q Subcomponent, B Chain; C1QD2; complement C1q
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-P71718
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QA; complement Component 1, Q Subcomponent, A Chain; complement C1q A Chain; complement C1q Chain A; complement C1q Subcomponent Subunit A; complement Component C1q, A Chain; complement Component 1, Q Subcomponent, Alpha Polypeptide; C1QD1
Species:  
Mouse
Source:  
P. pastoris
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1
1 Cited Publications
Cat. No.: HY-P73484
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading Factor; Serum-Spreading Factor; complement S-protein; Somatomedin B; S-protein; V75; Vitronectin (Serum Spreading Factor, Somatomedin B, complement S-protein); Epibolin; VNT
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7864
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700862
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78247
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding protein Li 62p; C3a; Acylation-Stimulating protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7535
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLU; complement-Associated protein SP-40,40; Prev. APOJ; complement Lysis Inhibitor; Prev. CLI; Ku70-Binding protein 1; Apolipoprotein J; NA1/NA2; TRPM-2; Clusterin (complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J); SGP-2; Epididymis Secretory Sperm Binding protein; KUB1; Aging-Associated Gene 4 protein; Testosterone-Repressed Prostate Message 2; Aging-Associated protein 4; Sulfated Glycoprotein 2; APO-J; SP-40; Apo-J; CLU2; SGP2; CLU1; AAG4; Clusterin; complement Cytolysis Inhibitor
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P9976
CAS No.: 1461640-62-9
Synonyms: ch38SB19; hu38SB19; SAR-650984

Target:  

CD38 Apoptosis

Research Areas:  

Cancer

Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38, a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions .
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1
1 Cited Publications
Cat. No.: HY-153229
Research Areas:  

Others

Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
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1
1 Cited Publications
Cat. No.: HY-P9976A
CAS No.: 1461640-62-9

Target:  

CD38 Apoptosis

Research Areas:  

Cancer

Isatuximab (anti-CD38) is a monoclonal antibody that targets the transmembrane receptor and extracellular enzyme CD38, a protein highly expressed in hematological malignancies, including multiple myeloma. Isatuximab (anti-CD38) exhibits anti-tumor activity through multiple biological mechanisms, including antibody-dependent cell-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cell phagocytosis, and non-crosslinking direct induction of apoptosis. Isatuximab (anti-CD38) also directly inhibits the extracellular enzyme activity of CD38, which is related to many cellular functions .
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1
1 Cited Publications
Cat. No.: HY-P7691
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD93; DJ737E23.1; Prev. C1QR1; ECSM3; Prev. MXRA4; Matrix-Remodeling-Associated protein 4; C1qR(P); Matrix-Remodelling Associated 4; CDw93; C1qR; complement Component 1 Q Subcomponent Receptor 1; complement Component 1, Q Subcomponent, Receptor 1; Complem
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P72137
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CFB; complement Factor B Preproprotein; Prev. BFD; Glycine-Rich Beta Glycoprotein; Prev. BF; C3 Proaccelerator; Properdin Factor B; C3 Proactivator; C3/C5 Convertase; ARMD14; H2-Bf; AHUS4; B-Factor, Properdin; FBI12; Properdin B; CFAB; PBF2; CFBD; GBG; FB
Species:  
Mouse
Source:  
E. coli
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