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cot

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P75921

    Mitogen-activated protein kinase kinase kinase 8; TPL-2; MAP3K8; cot; ESTF

    Human Sf9 insect cells
    MAP3K8/TPL-2 is critical for LPS-induced, TLR4-mediated activation of MAPK/ERK, leading to TNF production by macrophages. It regulates T cell differentiation, IFNG expression, and host resistance to bacterial infections by negatively regulating type I interferon production. MAP3K8/TPL-2 Protein, Human (sf9, GST) is the recombinant human-derived MAP3K8/TPL-2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MAP3K8/TPL-2 Protein, Human (sf9, GST) is 368 a.a., with molecular weight of ~68 kDa.
  • HY-P74218

    Peroxisomal carnitine O-octanoyltransferase; CROT; cot

    Human Sf9 insect cells
    CROT protein is critical in the β-oxidation process, showing the highest enzymatic activity on C6 to C10 substrates. As a key player in lipid metabolism, CROT promotes the conversion of 4,8-dimethylnonanoyl-CoA to its carnitine ester, regulating fatty acid oxidation to achieve cellular energy balance. CROT Protein, Human (V474L, sf9, His) is the recombinant human-derived CROT protein, expressed by Sf9 insect cells , with C-His labeled tag and V474L mutation.

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