10032 Results for "

evodiamine derivative conjugate

" in MedChemExpress (MCE) Product Catalog:
Products (10032)

10032 Results for "evodiamine derivative conjugate" in MCE Product Catalog:

168
168 Publications Verification
Cat. No.: HY-17031
CAS No.: 182410-00-0
Synonyms: Sulfobutylether-β-Cyclodextrin
SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents .
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99
99 Cited Publications
Cat. No.: HY-112675
CAS No.: 3133-16-2
Purity:  99.92%
Synonyms: 4-OI
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 .
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99
99 Cited Publications
Cat. No.: HY-17393
CAS No.: 41575-94-4
Synonyms: NSC 241240
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
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97
97 Cited Publications
Cat. No.: HY-15575
CAS No.: 646502-53-6
Purity:  99.94%
Synonyms: MC-Val-Cit-PAB-MMAE; mc-vc-PAB-MMAE; Vedotin
VcMMAE (mc-vc-PAB-MMAE) is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
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61
61 Cited Publications
Cat. No.: HY-15162
CAS No.: 474645-27-7
Purity:  99.97%
Synonyms: MMAE; SGD-1010
Research Areas:  

Cancer

Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
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61
61 Cited Publications
Cat. No.: HY-14650
CAS No.: 53-43-0
Purity:  99.93%
Synonyms: Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
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48
48 Cited Publications
Cat. No.: HY-D1374
CAS No.: 1144107-82-3
Sulfo-Cy5 carboxylic acid potassium is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
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39
39 Cited Publications
Cat. No.: HY-B1369
CAS No.: 74431-23-5
Synonyms: N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
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39
39 Cited Publications
Cat. No.: HY-B1369A
CAS No.: 64221-86-9
Synonyms: N-Formimidoyl thienamycin; MK0787
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
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33
33 Cited Publications
Cat. No.: HY-13631E
CAS No.: 1599440-13-7
Purity:  99.94%
Synonyms: MC-GGFG-DXD
Research Areas:  

Cancer

Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
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30
30 Cited Publications
Cat. No.: HY-19792
CAS No.: 139504-50-0
Synonyms: DM1; Maytansinoid DM1
Research Areas:  

Cancer

Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
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30
30 Cited Publications
Cat. No.: HY-B1511
CAS No.: 60-92-4
Synonyms: Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
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30
30 Cited Publications
Cat. No.: HY-B1511A
CAS No.: 37839-81-9
Synonyms: Cyclic adenosine monophosphate sodium; Adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .
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27
27 Cited Publications
Cat. No.: HY-15459
CAS No.: 183133-96-2
Purity:  99.91%
Synonyms: XRP6258; RPR-116258A; taxoid XRP6258
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
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25
25 Cited Publications
Cat. No.: HY-Y1890
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .
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25
25 Cited Publications
Cat. No.: HY-P0252
CAS No.: 581-05-5
Synonyms: α-Melanocyte-Stimulating Hormone
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .
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21
21 Cited Publications
Cat. No.: HY-N0324
CAS No.: 81-25-4
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .
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21
21 Cited Publications
Cat. No.: HY-N0324A
CAS No.: 361-09-1
Synonyms: Sodium cholate
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .
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20
20 Cited Publications
Cat. No.: HY-N0114
CAS No.: 518-17-2
Synonyms: (+)-evodiamine; d-evodiamine
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
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20
20 Cited Publications
Cat. No.: HY-19528
CAS No.: 979-92-0
Synonyms: SAH (S-Adenosylhomocysteine)
SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
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