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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1603 Results for "
surface
" in MedChemExpress (MCE) Product Catalog:
Products (1603)
1603 Results for "surface" in MCE Product Catalog:
51
51 Publications Verification
Synonyms: VX-445
Research Areas:
Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface .
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48 Cited Publications
Target:
Research Areas:
OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .
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45 Cited Publications
Cat. No.: HY-112847A
Purity: ≥98.0%
Synonyms: Sulfo-N-succinimidyl oleate sodium
Target:
Research Areas:
Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
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32 Cited Publications
Cat. No.: HY-P0023
CAS No.: 161552-03-0
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32 Cited Publications
Cat. No.: HY-P0023A
CAS No.: 500577-51-5
28
Tezacaftor (VX-661) is a F508del CFTR corrector. It helps CFTR protein reach the cell surface. However, Ivacaftor (VX-770, HY-13017), a CFTR potentiator, helps to prolong the opening time of cell surface CFTR protein channels. Tezacaftor combining with Ivacaftor, shows potent efficacy against cystic fibrosis and diseases with homozygous for the CFTR Phe508del mutation. Moreover, Elexacaftor (VX-445, HY-111772) is also a CFTR corrector. Elexacaftor-Tezacaftor-Ivacaftor aims at with cystic fibrosis (CF) with at least one Phe508del mutation, often avoids the indication for lung transplantation .
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Target:
Research Areas:
27
27 Cited Publications
Cat. No.: HY-P1363A
CAS No.: 107761-42-2
Synonyms: Amyloid β-peptide (1-42) (human)
Target:
Research Areas:
27
27 Cited Publications
Cat. No.: HY-P1363B
CAS No.: 107761-42-2
Target:
Research Areas:
26
26 Cited Publications
23
23 Cited Publications
Cat. No.: HY-D0802
CAS No.: 35013-72-0
Synonyms: Biotin N-hydroxysuccinimide ester; NHS-Biotin
23
Category:
Polysaccharides Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
Target:
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22 Cited Publications
Target:
Research Areas:
AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay .
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Target:
21
Category:
Zea mays L. Moisture Plants Endogenous metabolite Human Gut Microbiota Metabolites Polysaccharides Gramineae Cosmetic Research Disease Research Fields Saccharides Cancer
Target:
19
19 Cited Publications
Cat. No.: HY-W127378
CAS No.: 144189-73-1
Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
15
15 Cited Publications
Target:
Research Areas:
14
14
11
11 Cited Publications
Cat. No.: HY-D0986
CAS No.: 115534-33-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
