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Cat. No.: HY-142214

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TRPA1-IN-1

TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2376824-92-7
화학식: C₁₉H₁₇ClN₆O₃
분자량:412.83

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TRPA1-IN-1 Chemical Structure

CAS No.: 2376824-92-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.

All TRP Channel Isoforms :

Chemical Information

CAS No. 2376824-92-7
분자량 412.83
화학식 C₁₉H₁₇ClN₆O₃
SMILES

CN1C=NC2=C1C(N(C=N2)CC3=NC([C@@H]4CO[C@H](C4)C5=CC=C(C=C5)Cl)=NO3)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64(7):3843-38 [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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TRPA1-IN-1

All TRP Channel Isoforms