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Cat. No.: HY-142214

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TRPA1-IN-1

TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.

For research use only. We do not sell to patients.

CAS No.: 2376824-92-7
Formula: C₁₉H₁₇ClN₆O₃
Molecular Weight:412.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TRPA1-IN-1 Chemical Structure

CAS No.: 2376824-92-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.

All TRP Channel Isoforms :

Chemical Information

CAS No. 2376824-92-7
Molecular Weight 412.83
Formula C₁₉H₁₇ClN₆O₃
SMILES

CN1C=NC2=C1C(N(C=N2)CC3=NC([C@@H]4CO[C@H](C4)C5=CC=C(C=C5)Cl)=NO3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64(7):3843-38 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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TRPA1-IN-1

All TRP Channel Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TRPA1-IN-1 Related Classifications

HY-142214 Related Classifications

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Keywords

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