Wheat Germ Agglutinin (Biotinylated)

Wheat germ agglutinin (≥ 1 μg/mL; 1 ) agglutinates trypsinized rabbit erythrocytes at a minimum concentration of 1 μg/mL after 1 h incubation at 25 °C^[1].
Wheat germ agglutinin (30 min) undergoes endocytosis into Chinese hamster ovary (CHO) cells and leukemic Jurkat cells^[2].
Wheat germ agglutinin induces paraptosis in L929 murine fibroblast cells, characterized by vacuolation, loss of cell architecture, and upregulation of Bax and caspase-3, without classic apoptotic markers^[2].
Wheat germ agglutinin induces apoptosis in pancreatic carcinoma cells, characterized by chromatin condensation, nuclear fragmentation, and DNA release^[2].
Wheat germ agglutinin induces apoptosis in leukemic Jurkat cells via loss of transmembrane potential, mitochondrial membrane disruption, cytochrome c release, and caspase-9 activation^[2].
Wheat germ agglutinin suppresses proliferation of rat pancreatic acinar tumor (AR42J) cells by blocking auto-stimulation and inhibiting the trophic effects of glycosylated cholecystokinin or gastrin-like peptides^[2].
Wheat germ agglutinin enhances binding of fluorescein-labeled bull serum albumin to Caco-2 human colon adenocarcinoma cells by up to 8.7-fold, with 75% of binding being specific to WGA^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.