1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
    Anti-infection
    Apoptosis
    Autophagy
  2. GABA Receptor
    Reactive Oxygen Species
    Parasite
    Apoptosis
    Autophagy
  3. α-Thujone

α-Thujone 

Cat. No.: HY-121618
Handling Instructions

α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.

For research use only. We do not sell to patients.

α-Thujone Chemical Structure

α-Thujone Chemical Structure

CAS No. : 546-80-5

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier[1][2][3].

Molecular Weight

152.23

Formula

C₁₀H₁₆O

CAS No.

546-80-5

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

α-ThujoneGABA ReceptorReactive Oxygen SpeciesParasiteApoptosisAutophagyGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorMonoterpeneROSanti-tumorBBBoxidativestresspro-apoptoticanti-invasiveantinociceptiveinsecticidalanthelminticInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
α-Thujone
Cat. No.:
HY-121618
Quantity:
MCE Japan Authorized Agent: