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  3. GS-626510

GS-626510 

Cat. No.: HY-114416
Handling Instructions

GS-626510 is a potent, and orally bioavailable BET family bromodomains inhibitor, with Kd values of 0.59-3.2 nM for BRD2/3/4, with IC50 values of 83 nM and 78 nM foe BD1 and BD2, respectively.

For research use only. We do not sell to patients.

GS-626510 Chemical Structure

GS-626510 Chemical Structure

CAS No. : 1637770-13-8

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Description

GS-626510 is a potent, and orally bioavailable BET family bromodomains inhibitor, with Kd values of 0.59-3.2 nM for BRD2/3/4, with IC50 values of 83 nM and 78 nM foe BD1 and BD2, respectively[1].

IC50 & Target[1]

BRD2

0.59-2.5 nM (Kd)

BRD3

0.65-0.66 nM (Kd)

BRD4

1.3-3.2 nM (Kd)

BD1

83 nM (IC50)

BD2

78 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

394.47

Formula

C₂₅H₂₂N₄O

CAS No.

1637770-13-8

SMILES

CC1=C(C2=CC(C3=C4C=CC=NC4=CC=C3C)=C5NC(C6CC6)=NC5=C2)C(C)=NO1

Shipping

Room temperature in continental US; may vary elsewhere

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GS-626510
Cat. No.:
HY-114416
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GS-626510

Cat. No.: HY-114416