1. GPCR/G Protein Neuronal Signaling
  2. 5-HT Receptor
  3. NAN-190 hydrobromide

NAN-190 hydrobromide 

Cat. No.: HY-19818A Purity: 98.59%
COA Handling Instructions

NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.

For research use only. We do not sell to patients.

NAN-190 hydrobromide Chemical Structure

NAN-190 hydrobromide Chemical Structure

CAS No. : 115338-32-4

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 73 In-stock
Solution
10 mM * 1 mL in DMSO USD 73 In-stock
Solid
5 mg USD 42 In-stock
10 mg USD 66 In-stock
50 mg USD 92 In-stock
100 mg USD 119 In-stock
200 mg USD 211 In-stock
500 mg   Get quote  
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of NAN-190 hydrobromide:

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  • Biological Activity

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Description

NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A[1][3].

IC50 & Target[1]

5-HT1 Receptor

 

In Vivo

NAN-190 hydrobromide (0.5 mg/kg, ip) is injected concomitantly with the effective dose of fluoxetine. NAN-190 reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

474.39

Formula

C23H28BrN3O3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N(CCCCN2CCN(C3=CC=CC=C3OC)CC2)C(C4=C1C=CC=C4)=O.[H]Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (35.14 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1080 mL 10.5399 mL 21.0797 mL
5 mM 0.4216 mL 2.1080 mL 4.2159 mL
10 mM 0.2108 mL 1.0540 mL 2.1080 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.67 mg/mL (3.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1.67 mg/mL (3.52 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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NAN-190 hydrobromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
NAN-190 hydrobromide
Cat. No.:
HY-19818A
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