2. Inflammation/Immunology

Inflammation/Immunology (炎症/免疫)

Inflammation/Immunology

関連製品

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-W335927
    MAO-B-IN-19 152897-41-1 98%
    MAO-B-IN-19 is a selective MAO-B inhibitor with an IC50 of 0.67 μM. MAO-B-IN-19 shows neuroprotective and anti-inflammatory properties.
    MAO-B-IN-19
  • HY-W338346
    Salicylate choline 2016-36-6 98%
    Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer.
    Salicylate choline
  • HY-W339645
    Naproxen ethyl ester 31220-35-6 98%
    Naproxen ethyl ester ((S)-Naproxen ethyl ester) is a nonsteroidal anti-inflammatory drug with activity in relieving pain, fever, swelling and stiffness. Naproxen ethyl ester exerts its effects by inhibiting non-selective cyclooxygenase (COX). The R-(-)-isomer of Naproxen ethyl ester shows stronger immunogenicity, and the Michaelis-Menten parameter of its catalytic reaction is K(M)=6.67 mM, and the catalytic efficiency is 5.8 x 10^4 times higher than that of the non-catalytic reaction.
    Naproxen ethyl ester
  • HY-W342853
    HPSE-IN-1 58954-23-7 98%
    HPSE-IN-1 (Compound 31) is a heparanase inhibitor with an IC50 of 970 µM. HPSE-IN-1 can be used in the research of inflammatory diseases and cancer.
    HPSE-IN-1
  • HY-W344531
    Indomethacin glucuronide 75523-11-4 98%
    Indomethacin glucuronide is a glucuronide metabolite of Indomethacin (HY-14397).
    Indomethacin glucuronide
  • HY-W345148
    2-Naphthylamine-6,8-disulfonic acid potassium 842-15-9 98%
    2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc.
    2-Naphthylamine-6,8-disulfonic acid potassium
  • HY-W357142
    3-Acetylumbelliferyl β-D-Glucopyranoside 20943-16-2 98%
    3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase.
    3-Acetylumbelliferyl β-D-Glucopyranoside
  • HY-W371164
    C1s-IN-1 1016866-61-7 98%
    C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a Kd of 9.8 μM.
    C1s-IN-1
  • HY-W385577
    (S)-2-Benzylpyrrolidine 97522-31-1 98%
    (S)-2-Benzylpyrrolidine (Compound s1) serves as a METH hapten scaffold. (S)-2-Benzylpyrrolidine attenuates Methamphetamine-induced hyperlocomotion, hyperthermia and respiratory depression. (S)-2-Benzylpyrrolidine alleviates Fentanyl-induced respiratory depression.
    (S)-2-Benzylpyrrolidine
  • HY-W387035
    D-α-Methyl DOPA 2799-15-7 98%
    D-α-Methyl DOPA is an inhibitor of the binding of DQ8 peptide to MHC class II molecules. D-α-Methyl DOPA occupies a pocket along the DQ8 peptide binding groove. D-α-Methyl DOPA inhibits the binding of a DQ8 peptide to an MHC class II molecule for presentation to CD4+ T cells, thereby slowing the development or progression of type 1 diabete or celiac disease.
    D-α-Methyl DOPA
  • HY-W392413
    Glutathione monoethyl ester 118421-50-4 98%
    Glutathione monoethyl ester is a glutathione derivative that can be transported into cells and hydrolyzed into glutathione. Glutathione monoethyl ester downregulates the gene expression of TEN1 and CTC1 while upregulating TERT expression. Glutathione monoethyl ester enhances telomerase activity, promotes proliferation and differentiation in aged bone marrow stromal cells, while elevating glutathione levels and reducing oxidative stress, protein aggregation and cell death in motor neuronal cells. Glutathione monoethyl ester confers broad multi-organ protection against cerebral ischemia, renal injury, liver damage, and pancreatitis. Glutathione monoethyl ester can be used for the research of amyotrophic lateral sclerosis, stroke, acute renal failure, liver injury, and acute pancreatitis.
    Glutathione monoethyl ester
  • HY-W403075
    N-(3-Methoxybenzyl)stearamide 1429659-99-3 98.04%
    N-(3-Methoxybenzyl)stearamide a natural product from Lepidium meyenii (Maca), inhibits human and mouse soluble epoxide hydrolase (hsEH and msEH) with IC50s of 0.001 and <0.001 μg/nM, respectively.
    N-(3-Methoxybenzyl)stearamide
  • HY-W415753
    Alaptide 90058-29-0 98%
    Alaptide, a spirocyclic synthetic dipeptide and a derivative of melanocyte-stimulating hormone release-inhibiting factor (MIF), is a transdermal permeation modifier. Alaptide loaded on nanofibrous membranes accelerates the healing of skin incisions, particularly the healing of skin burns. Alaptide is a nootropic agent, that influences the dopaminergic system and increases homovanillic acid level in the striatum of rat models. Alaptide can be used for wound healing with large damaged areas and neurological diseases research.
    Alaptide
  • HY-W420454
    Danshenspiroketallactone 100414-80-0 98%
    Danshenspiroketallactone is a lactone found in the roots of Salvia miltiorrhiza. Danshenspiroketallactone shows no anti-inflammatory and anticancer activity.
    Danshenspiroketallactone
  • HY-W424539
    Prednisolone sodium succinate 1715-33-9 98%
    Prednisolone (sodium succinate) is an anti-inflammatory corticosteroid and a prodrug of the glucocorticoid prednisolone. Prednisolone (sodium succinate) is used as an immunosuppressant.
    Prednisolone sodium succinate
  • HY-W424851
    DPQ hydrochloride 84050-22-6 98%
    DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-κB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-α, IL-6) and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases.
    DPQ hydrochloride
  • HY-W436270
    Bulbocapnine hydrochloride 632-47-3 98%
    Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor. Bulbocapnine hydrochloride inhibits dopamine synthesis. Bulbocapnine hydrochloride also has neuroleptic-like, anticonvulsant and antinociceptive effects.
    Bulbocapnine hydrochloride
  • HY-W472153
    β-Glucuronidase-IN-5 7455-77-8 98%
    β-Glucuronidase-IN-5 (Compound 19; Compound 5c) is a β-glucuronidase inhibitor with an IC50 of 39.8 μM. β-Glucuronidase-IN-5 does not show significant cytotoxicity towards PC-3 cells, with its IC50 > 30 μM. β-Glucuronidase-IN-5 shows no affinity for adenosine receptors (A₁ and A₂A receptors). β-Glucuronidase-IN-5 can be used to study diseases related to excessive expression of β-glucuronidase (such as colon cancer, arthritis, and AIDS complications).
    β-Glucuronidase-IN-5
  • HY-W472451
    Linalyl isobutyrate 78-35-3 98%
    Linalyl isobutyrate is a fragrance ingredient. Linalyl isobutyrate produces very slight erythema.
    Linalyl isobutyrate
  • HY-W474473
    3-(N-Phthalimidoylmethylthio)propanoic acid 91570-07-9 98%
    3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid (MFP) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid can be combined with carrier proteins and used in antigen design.
    3-(N-Phthalimidoylmethylthio)propanoic acid
製品番号 製品名 / Synonyms Application Reactivity