Revexepride
Based on 1 publication(s) in Google Scholar
Revexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 219984-49-3
- Formula: C21H32ClN3O4
- Molecular Weight:425.95
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Revexepride
MoreAll 5-HT Receptor Isoforms
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Biological Activity
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5-HT4 Receptor |
CYP3A4 |
The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC50 values of 16-49 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 219984-49-3
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Appearance Solid
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Molecular Weight 425.95
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Formula C21H32ClN3O4
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Color White to yellow
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SMILES
O=C(C1=C(OC(C)(C)C2)C2=C(N)C(Cl)=C1)NC[C@H]3[C@H](O)CN(CCCOC)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : ≥ 100 mg/mL (234.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3477 mL | 11.7385 mL | 23.4769 mL | 58.6923 mL |
| 5 mM | 0.4695 mL | 2.3477 mL | 4.6954 mL | 11.7385 mL | |
| 10 mM | 0.2348 mL | 1.1738 mL | 2.3477 mL | 5.8692 mL | |
| 15 mM | 0.1565 mL | 0.7826 mL | 1.5651 mL | 3.9128 mL | |
| 20 mM | 0.1174 mL | 0.5869 mL | 1.1738 mL | 2.9346 mL | |
| 25 mM | 0.0939 mL | 0.4695 mL | 0.9391 mL | 2.3477 mL | |
| 30 mM | 0.0783 mL | 0.3913 mL | 0.7826 mL | 1.9564 mL | |
| 40 mM | 0.0587 mL | 0.2935 mL | 0.5869 mL | 1.4673 mL | |
| 50 mM | 0.0470 mL | 0.2348 mL | 0.4695 mL | 1.1738 mL | |
| 60 mM | 0.0391 mL | 0.1956 mL | 0.3913 mL | 0.9782 mL | |
| 80 mM | 0.0293 mL | 0.1467 mL | 0.2935 mL | 0.7337 mL | |
| 100 mM | 0.0235 mL | 0.1174 mL | 0.2348 mL | 0.5869 mL |
Revexepride Related Classifications
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