Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
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Drug Metabolite Related Products (2022)
Related Products (2022)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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13-cis Acitretin-d3
0 ImagesCat. No.: HY-129240SCAS No.: 1185241-03-5Synonyms: Isoacitretin d3; Ro 13-7652 d313-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
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Tauro-obeticholic acid-d5 sodium
0 ImagesCat. No.: HY-135399STauro-obeticholic acid-d5 sodium is deuterium labeled Tauro-obeticholic acid sodium (HY-135399A). Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.
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m-Nifedipine (Standard)
0 Imagesm-Nifedipine (Standard) is the analytical standard of m-Nifedipine. This product is intended for research and analytical applications. m-Nifedipine is an impurity of Nifedipine (BAY-a-1040). Nifedipine is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
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4-Oxoetodolac
0 ImagesCat. No.: HY-W740009CAS No.: 111478-86-54-Oxoetodolac, Etodolac (HY-76251) metabolite, is an orally active antiinflammatory agent. 4-Oxoetodolac blocks prostaglandin production in cultured chondrocyte cells. 4-Oxoetodolac exhibits slight antiinflammatory activity in a rat adjuvant edema model. 4-Oxoetodolac can be used for the research of inflammation.
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Desloratadine-d4 hydrobromide
0 ImagesCat. No.: HY-B0539S4Synonyms: Sch34117-d4 hydrobromideDesloratadine-d4 hydrobromide is deuterated labeled Desloratadine (HY-B0539). Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.
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Cilinaphthalide B
0 ImagesCat. No.: HY-N21713CAS No.: 102040-06-2Cilinaphthalide B is an integrin αIIbβ3 inhibitor and a phthalide derivative that inhibits platelet aggregation by binding to integrin αIIbβ3 and interfering with the conformational changes required for its activation, and it exhibits cytotoxicity against cancer cell lines. Cilinaphthalide B can be used in antiplatelet and anticancer-related research.
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Eoxin E4
0 ImagesCat. No.: HY-115356CAS No.: 1000852-57-2Synonyms: 14,15-LTE4; EoxE4Eoxin E4 (14,15-LTE4) is the metabolite of 14,15-LTC4 and 14,15-LTD4. Eoxin E4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine.
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Atorvastatin Epoxy Tetrahydrofuran Impurity
0 ImagesAtorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
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N-Desethyl Bimatoprost
0 ImagesCat. No.: HY-B0191CCAS No.: 155205-89-3
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4-Hydroxyechinenone
0 ImagesCat. No.: HY-W750707CAS No.: 2213-17-44-Hydroxyechinenone is a trace carotenoid present in the carapaces of crabs. 4-Hydroxyechinenone is also an intermediate in the metabolism of β-Carotene (HY-N0411) to Astaxanthin (HY-B2163).
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L 691121 free base
0 ImagesCat. No.: HY-180335CAS No.: 136075-61-1L 691121 (free base) is the major metabolite of L 691121 in plasma. L 691121 (free base) is a class IIIantiarrhythmic agent that blocks potassium currents.
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Febuxostat 67M-1
0 ImagesCat. No.: HY-131321CAS No.: 887945-96-2Febuxostat 67M-1 is an active metabolite of Febuxostat (HY-14268). Febuxostat 67M-1 retains inhibitory activity against Xanthine Oxidase, but its plasma concentration is much lower than that of Febuxostat. Febuxostat 67M-1 can be used in the research of hyperuricemia.
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ABZ-amine (Standard)
0 ImagesCat. No.: HY-135410RCAS No.: 80983-36-4Synonyms: Amino albendazole (Standard)ABZ-amine (Standard) is the analytical standard of ABZ-amine. This product is intended for research and analytical applications. ABZ-amine (Amino albendazole) is an impurity of Albendazole. Albendazole is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations.
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Abiraterone sulfate-d4 sodium
0 ImagesCat. No.: HY-144953S
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2-Hydroxy atorvastatin-d5
0 ImagesCat. No.: HY-141987SCAS No.: 777841-55-1Synonyms: Atorvastatin impurity K-d52-Hydroxy atorvastatin-d5 (Atorvastatin impurity K-d5) is the deuterium labeled 2-Hydroxy atorvastatin. 2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
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Desloratadine (Standard)
0 ImagesSynonyms: Sch34117 (Standard)Desloratadine (Standard) is the analytical standard of Desloratadine. This product is intended for research and analytical applications. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.
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N,N,O-Tridesmethylvenlafaxine (Standard)
0 ImagesCat. No.: HY-W049735RCAS No.: 149289-29-2Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes-.
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4-Hydroxyantipyrine (Standard)
0 ImagesSynonyms: 4-Hydroxyphenazone (Standard); NSC 174055 (Standard)4-Hydroxyantipyrine (Standard) is the analytical standard of 4-Hydroxyantipyrine. This product is intended for research and analytical applications. 4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain.
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Betahistine impurity 5-13C,d3
0 ImagesCat. No.: HY-143925SBetahistine impurity 5-13C,d3 is the 13C- and deuterium labeled Betahistine impurity 5.
