Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2569)
Related Products (2569)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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HSP90-IN-21
0 ImagesCat. No.: HY-153547CAS No.: 2521791-38-6HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively.
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Plm IV inhibitor-2
0 ImagesCat. No.: HY-148035CAS No.: 1539276-38-4Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites.
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Antileishmanial agent-26
0 ImagesCat. No.: HY-161325Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with anti-Leishmania donovani activity. Its IC50 value against Leishmania donovani is 5.67 μM, and its CC50 value against THP-1 is 3.79 μM. Antileishmanial agent-26 can be used in the research of tropical diseases.
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20S Proteasome-IN-4
0 ImagesCat. No.: HY-151195CAS No.: 2827061-47-020S Proteasome-IN-4 (Compound 7) is a brain-penetrant, parasite-selective, orally active 20S proteasome inhibitor with an IC50 of 6.3 nM against T. b. brucei 20S proteasome. 20S Proteasome-IN-4 can be used for the research of human African trypanosomiasis (HAT).
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Nequinate
0 ImagesCat. No.: HY-116433CAS No.: 13997-19-8Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
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Erythromycin B
0 ImagesCat. No.: HY-W779377CAS No.: 527-75-3Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum.
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Methylclonazepam
0 ImagesCat. No.: HY-W399186CAS No.: 5527-71-9Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
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Hypocrellin B (Standard)
0 ImagesCat. No.: HY-N1453RCAS No.: 123940-54-5Hypocrellin B (Standard) is the analytical standard of Hypocrellin B. This product is intended for research and analytical applications. Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3].
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Juncin E
0 ImagesCat. No.: HY-126744CAS No.: 129602-22-8Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm[2].
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Nifursol (Standard)
0 ImagesNifursol (Standard) is the analytical standard of Nifursol (HY-B1703). This product is used for research and analytical applications. Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals.
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Cardol diene
0 ImagesCat. No.: HY-118495CAS No.: 79473-25-9Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability.
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TCMDC-136230
0 ImagesCat. No.: HY-132930CAS No.: 3015474-48-0TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
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Virustomycin A
0 ImagesCat. No.: HY-126571CAS No.: 84777-85-5Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity.
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Euquinine
0 ImagesEuquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .
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Quinine sulfate hydrate (Standard)
0 ImagesCat. No.: HY-W010668RCAS No.: 6119-70-6Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
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Antimalarial agent 51
0 ImagesCat. No.: HY-176223Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC). Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel.
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Palmarumycin C3
0 ImagesCat. No.: HY-N10263CAS No.: 159934-11-9Palmarumycin C3 is a spirobisnaphthalene compound isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. Palmarumycin C3 exhibits stronger antimicrobial and antioxidant activities.
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Bulaquine
0 ImagesCat. No.: HY-106866CAS No.: 79781-00-3Synonyms: CDRI 80/53; ElubaquineBulaquine (CDRI 80/53) is a potent antimalarial agent which is an analogue of Primaquine (HY-12651A). Bulaquine affects multiple metabolism pathways and shows inhibition effect on Plasmodium cynomolgi infection. Bulaquine can be used for the research of malaria.
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Antileishmanial agent-40
0 ImagesCat. No.: HY-183262CAS No.: 3126462-40-3Antileishmanial agent-40 is an orally active and selective antileishmanial agent. Antileishmanial agent-40 elevates intracellular reactive oxygen species (ROS) levels in Leishmania donovani promastigotes. Antileishmanial agent-40 induces cell cycle arrest at the sub-G0/G1 phase in Leishmania donovani promastigotes, indicative of programmed-like parasite death. Antileishmanial agent-40 can be used for the research of leishmaniasis.
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Pimozide-d4-1
0 ImagesCat. No.: HY-12987S2Synonyms: R6238-d4-1Pimozide-d4-1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
