Ac-IEPD-AFC
Based on 1 publication(s) in Google Scholar
Ac-IEPD-AFC is a substrate of Granzyme B.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 1135417-31-0
- Formula: C32H38F3N5O11
- Molecular Weight:725.67
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) Ac-IEPD-AFC
MoreAll Caspase Isoforms
More
Biological Activity
The Km of human granzyme B for Ac-IEPD-AFC in granzyme B assay buffer is 585 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1135417-31-0
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Appearance Solid
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Molecular Weight 725.67
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Formula C32H38F3N5O11
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Color White to off-white
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Sequence Shortening
Ac-IEPD-AFC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
2025 Jan 31;16(1):1233. PMID: 39890804
Solvent & Solubility
DMSO : 100 mg/mL (137.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3780 mL | 6.8902 mL | 13.7804 mL | 34.4509 mL |
| 5 mM | 0.2756 mL | 1.3780 mL | 2.7561 mL | 6.8902 mL | |
| 10 mM | 0.1378 mL | 0.6890 mL | 1.3780 mL | 3.4451 mL | |
| 15 mM | 0.0919 mL | 0.4593 mL | 0.9187 mL | 2.2967 mL | |
| 20 mM | 0.0689 mL | 0.3445 mL | 0.6890 mL | 1.7225 mL | |
| 25 mM | 0.0551 mL | 0.2756 mL | 0.5512 mL | 1.3780 mL | |
| 30 mM | 0.0459 mL | 0.2297 mL | 0.4593 mL | 1.1484 mL | |
| 40 mM | 0.0345 mL | 0.1723 mL | 0.3445 mL | 0.8613 mL | |
| 50 mM | 0.0276 mL | 0.1378 mL | 0.2756 mL | 0.6890 mL | |
| 60 mM | 0.0230 mL | 0.1148 mL | 0.2297 mL | 0.5742 mL | |
| 80 mM | 0.0172 mL | 0.0861 mL | 0.1723 mL | 0.4306 mL | |
| 100 mM | 0.0138 mL | 0.0689 mL | 0.1378 mL | 0.3445 mL |