1192U90
1192U90 is an antipsychotic agent, dopamine D2 receptor antagonist as well as serotonin 5-HT1a receptor agonist. 1192U90 reduces the number of spontaneously firing neurons in the limbic dopamine system.
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- CAS. Nr.: 155289-31-9
- Formel: C22H27N5OS
- Molecular Weight:409.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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D2 Receptor |
5-HT1A Receptor |
Chemical Information
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CAS. Nr. 155289-31-9
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Molecular Weight 409.55
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Formel C22H27N5OS
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SMILES
O=C(C1=C(C=CC=C1)N)NCCCCN2CCN(C3=NSC4=C3C=CC=C4)CC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Dillberger JE, et al. The experimental antipsychotic agent 1192U90 targets tapetum lucidum in canine eyes. Toxicol Pathol. 1996 Sep-Oct;24(5):595-601. [Content Brief]
[2]. Norman MH, et al. Structure-activity relationships of a series of substituted benzamides: potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents. J Med Chem. 1996 Mar 1;39(5):1172-88. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)