PROTAC CG167
PROTAC CG167 is a selective and potent CypA PROTAC degrader. PROTAC CG167 degrades CypA in a dose-dependent manner (Jurkat: DC50: 123 nM). PROTAC CG167 can inhibit HIV-1 and HCV and exhibits antiviral activity. (Pink: CypA Ligand (HY-170997); Black: Linker (HY-W123015); Blue: E3 Ligase Ligand (HY-112078))
(Pink: CypA ligand (HY-170997 ); Blue: VHL ligand (HY-112078); Black: linker (HY-W123015)).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C65H79N13O11S
- Molecular Weight:1250.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cyclophilin A 123 nM (DC50) |
HIV-1 |
Chemical Information
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Molecular Weight 1250.47
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Formel C65H79N13O11S
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SMILES
CC1=C(C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C([C@@H](NC(CCCCCN4N=NC(CCC[C@@H](OC([C@H]5NN(CCC5)C([C@H](C)NC([C@@H](NC(C/C=C/6)=O)CC7=CC=C(C=C7)[N+]([O-])=O)=O)=O)=O)C8=CC=C9C=CC6=CC9=N8)=C4)=O)C(C)(C)C)=O)O)=O)C)SC=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PROTAC CG167 Related Classifications
HY-173009 Related Classifications
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