BRD9 Degrader-2
BRD9 Degrader-2 is a selective BRD9 molecular glue degrader. BRD9 Degrader-2 consists of a BRD9-binding ligand, a linker, and a warhead that promotes proteasomal degradation of BRD9 via a non-canonical PROTAC mechanism independent of CRBN or VHL E3 ligases. BRD9 Degrader-2 can be used in cancer research, including studies of malignant rhabdoid tumors, specific sarcomas, and acute myeloid leukemia.
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- CAS No.: 3033018-68-4
- Formule: C40H43F3N6O4S
- Masse moléculaire:760.87
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
BRD9 ≤1.25 nM (DC50) |
In Vitro
Chemical Information
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CAS No. 3033018-68-4
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Masse moléculaire 760.87
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Formule C40H43F3N6O4S
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SMILES
N#C/C(C(N1CCC2=C(C1C)C=CC=C2CN3CCN(CC3)CC4=C(OC)C=C(C5=CN(C)C(C(C)=C5C)=O)C=C4OC)=O)=C\C6=NC(C(F)(F)F)=CS6
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD9 Degrader-2 Related Classifications
HY-163809 Related Classifications
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