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Cat. No.: HY-101225A

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8 Hydroxy PIPAT

8 Hydroxy PIPAT is a 5-HT_1A receptor agonist that promotes histamine release. 8 Hydroxy PIPAT selectively activates 5-HT_1A receptors, thereby triggering mast cell degranulation and histamine release. 8 Hydroxy PIPAT is applicable to research related to irritable bowel syndrome.

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CAS No.: 159651-91-9
Formule: C₁₆H₂₂INO
Masse moléculaire:371.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

8 Hydroxy PIPAT Chemical Structure

CAS No.: 159651-91-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

IC₅₀ & Target^[1]

5-HT_1A Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

Voir tous les produits spécifiques à Isoform Histamine Receptor :

In Vitro

8 Hydroxy PIPAT oxalate (20 µM; 10 min) potently stimulates histamine release from full-thickness human jejunal segments via activation of 5-HT_1A receptors^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 159651-91-9
Masse moléculaire 371.26
Formule C₁₆H₂₂INO
SMILES

OC1=C2C(CCC(N(C/C=C/I)CCC)C2)=CC=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wang GD, et al. Mast cell expression of the serotonin1A receptor in guinea pig and human intestine. Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G855-63.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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8 Hydroxy PIPAT

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Voir tous les produits spécifiques à Isoform Histamine Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

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8 Hydroxy PIPAT Related Classifications

HY-101225A Related Classifications