Tudociclib
Based on 1 Customer Validation
Tudociclib is a CDK2 inhibitor with an IC50 value ≤20 nM. Tudociclib modulates CDK2 activity to influence cell cycle regulation. Tudociclib can be used for the research of cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.40%
- CAS No.: 2640038-22-6
- Formule: C18H25N7O3S
- Masse moléculaire:419.50
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK2 ≤ 20 nM (IC50) |
Tudociclib (Compound Formula (I)) (1 h) potently inhibits CDK2/Cyclin E1 enzyme activity with an IC50 value ≤20 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2640038-22-6
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Appearance Solid
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Masse moléculaire 419.50
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Formule C18H25N7O3S
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Color White to off-white
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SMILES
CCOC1=C(C2=CNN=C2)C=CN3C1=NC(N[C@@H]4[C@@H](CN(CC4)S(C)(=O)=O)C)=N3
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Synonyms
CDK2-IN-30
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (238.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3838 mL | 11.9190 mL | 23.8379 mL | 59.5948 mL |
| 5 mM | 0.4768 mL | 2.3838 mL | 4.7676 mL | 11.9190 mL | |
| 10 mM | 0.2384 mL | 1.1919 mL | 2.3838 mL | 5.9595 mL | |
| 15 mM | 0.1589 mL | 0.7946 mL | 1.5892 mL | 3.9730 mL | |
| 20 mM | 0.1192 mL | 0.5959 mL | 1.1919 mL | 2.9797 mL | |
| 25 mM | 0.0954 mL | 0.4768 mL | 0.9535 mL | 2.3838 mL | |
| 30 mM | 0.0795 mL | 0.3973 mL | 0.7946 mL | 1.9865 mL | |
| 40 mM | 0.0596 mL | 0.2980 mL | 0.5959 mL | 1.4899 mL | |
| 50 mM | 0.0477 mL | 0.2384 mL | 0.4768 mL | 1.1919 mL | |
| 60 mM | 0.0397 mL | 0.1986 mL | 0.3973 mL | 0.9932 mL | |
| 80 mM | 0.0298 mL | 0.1490 mL | 0.2980 mL | 0.7449 mL | |
| 100 mM | 0.0238 mL | 0.1192 mL | 0.2384 mL | 0.5959 mL |
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