CDK2-IN-53
CDK2-IN-53 (compound 9) is a CDK2 inhibitor with anticancer activity. CDK2-IN-53 selectively inhibits the proliferation of HCT-116 and MCF-7cells with IC50 values of 13.89 and 7.65 μM, respectively, while showing lower cytotoxicity toward normal lung fibroblast (WI-38) cells (IC50 = 71.24 μM). CDK2-IN-53 can be used for cancer research, such as colon and breast cancer.
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- Formule: C27H23ClN6O2S
- Masse moléculaire:531.03
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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CDK2 |
Chemical Information
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Masse moléculaire 531.03
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Formule C27H23ClN6O2S
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SMILES
ClC(N(N=C1C)C2=CC=CC=C2)=C1/C=C(C(NNC(NC3=CC=CC=C3)=S)=O)\NC(C4=CC=CC=C4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)