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Lactic acid sodium (60% w/w in water)

(Synonyms: DL-Lactic acid sodium; E-270 sodium)
63 Cited Publications
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Based on 63 publication(s) in Google Scholar

Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative.
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).

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  • Pureté: 98.0%
  • CAS No.: 72-17-3
  • Formule: C3H5NaO3
  • Masse moléculaire:112.06
  • Stockage:

    Solution, -20°C, 2 years

  • Lactic acid sodium (60% w/w in water) Chemical Structure
    Lactic acid sodium (60% w/w in water) Chemical Structure
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
  • Experimental Validation Results for Lactic acid sodium (60% w/w in water)
CAS No.: 72-17-3
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  • Lactic acid sodium (60% w/w in water) Chemical Structure
    Lactic acid sodium (60% w/w in water) Chemical Structure
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    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 29:e09477. [Abstract]

    Customer Validation
     Following the direct addition of lactic acid (a final concentration of 100 mM) to the culture medium for 12 h, western blotting, and immunoprecipitation assays revealed a significant increase in the total lactylation and corresponding lysine-312 lactylation levels in ASH2L

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 27:e2413709. [Abstract]

    Customer Validation
     Western blot of UGDH lactylation in chondrocytes with Lactic acid sodium (lactate) (25 mM) treatment for 24 h.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Apr:81:103553. [Abstract]

    Customer Validation
     Immunoblot and quantification analyses of NFS1 in HCC cells incubated with 0, 5, or 10 mM lactate after being subjected to either a 47 °C or 37 °C water bath.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Mar 20;16(1):193. [Abstract]

    Customer Validation
     Lactate sodium (5-15 mM; 24 h) ​​results​​ in increased H4K12la (red) levels in CCSCs compared to the control group.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144. [Abstract]

    Customer Validation
     Lactate (25 mM) significantly increases the mRNA and protein expression of FBXO33.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144. [Abstract]

    Customer Validation
     Co-IP detected the effect of lactate on YY1 protein lactylation modification.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2024 Mar 5;43(1):68. [Abstract]

    Customer Validation
     Lactate sodium increases IGF-1R levels in PI-resistant KAS-6/1 and U266 cells.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: Cell Res. 2023 Sep;33(9):679-698. [Abstract]

    Customer Validation
     Lactate (NALA) (300 mM; 24 h) significantly upregulates α-MHC K1897 lactylation in H9c2 cells.

  • 1/16

    Lactic acid sodium (60% w/w in water) purchased from MedChemExpress. Usage Cited in: J Ginseng Res. 2024 May;48(3):298-309. [Abstract]

    Customer Validation
     The expression level of METTL3, YTHDF1, YTHDF2, and YTHDC1 in NB4-R1 and NB4-R2 cells treated with 20 μM oxamate or 20 μM lactate or 1 μM ATRA for 48 h was detected via qRT-PCR.

  • Lactic acid sodium (60% w/w in water)