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Cat. No.: HY-14155

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MMP145

MMP145 (compound 27) is a potent, selective and orally active MMP-12 inhibitor. MMP145 is effective in inflammation and asthma reasearch.

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CAS No.: 1025717-75-2
Formule: C₂₀H₂₀N₂O₇S
Masse moléculaire:432.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

MMP145 Chemical Structure

CAS No.: 1025717-75-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

MMP145 (compound 27) is a potent, selective and orally active MMP-12 inhibitor. MMP145 is effective in inflammation and asthma reasearch^[1].

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Chemical Information

CAS No. 1025717-75-2
Masse moléculaire 432.45
Formule C₂₀H₂₀N₂O₇S
SMILES

CC(C)[C@@H](C(O)=O)NS(=O)(C1=CC=C(C2=CC(N3C(OCC3)=O)=CC=C2O4)C4=C1)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wei Li,Jianchang Li,Yuchuan Wu,Fabio Rancati,Stefania Vallese,Luca Raveglia ,Junjun Wu ,Rajeev Hotchandani,Nathan Fuller,Kristina Cunningham ,Paul Morgan ,Susan Fish,Rustem Krykbaev , Xin Xu , Steve Tam , Samuel J. Goldman , William Abraham , Cara Williams,Joseph Sypek and Tarek S.Mansour.Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of AsthmaJ. Med. Chem., 2009, 52 (17), pp 5408–5419.

[2]. Li W, et, al. Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma. J Med Chem. 2009 Sep 10;52(17):5408-19. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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MMP145

Voir tous les produits spécifiques à Isoform MMP

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

MMP145 Related Classifications

HY-14155 Related Classifications