SW2_152F
Based on 1 Customer Validation
SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a Kd of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro. SW2_152F is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- Pureté: 99.51%
- Formule: C45H62Cl3N7O8
- Masse moléculaire:935.37
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Stockage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Kd: 80 nM (chromobox 2 chromodomain)[1]
Chemical Information
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Appearance Solid
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Masse moléculaire 935.37
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Formule C45H62Cl3N7O8
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Color White to off-white
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SMILES
ClC1=CC(Cl)=CC(C(N[C@@H](CC2=CC(Cl)=C(O)C=C2)C(N[C@@H](C3CCCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(NCC#C)=O)=O)=O)=O)=O)=O)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
DMSO : 175 mg/mL (187.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0691 mL | 5.3455 mL | 10.6910 mL | 26.7274 mL |
| 5 mM | 0.2138 mL | 1.0691 mL | 2.1382 mL | 5.3455 mL | |
| 10 mM | 0.1069 mL | 0.5345 mL | 1.0691 mL | 2.6727 mL | |
| 15 mM | 0.0713 mL | 0.3564 mL | 0.7127 mL | 1.7818 mL | |
| 20 mM | 0.0535 mL | 0.2673 mL | 0.5345 mL | 1.3364 mL | |
| 25 mM | 0.0428 mL | 0.2138 mL | 0.4276 mL | 1.0691 mL | |
| 30 mM | 0.0356 mL | 0.1782 mL | 0.3564 mL | 0.8909 mL | |
| 40 mM | 0.0267 mL | 0.1336 mL | 0.2673 mL | 0.6682 mL | |
| 50 mM | 0.0214 mL | 0.1069 mL | 0.2138 mL | 0.5345 mL | |
| 60 mM | 0.0178 mL | 0.0891 mL | 0.1782 mL | 0.4455 mL | |
| 80 mM | 0.0134 mL | 0.0668 mL | 0.1336 mL | 0.3341 mL | |
| 100 mM | 0.0107 mL | 0.0535 mL | 0.1069 mL | 0.2673 mL |
SW2_152F Related Classifications
HY-147058 Related Classifications
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