YSY01A
YSY01A is a proteasome inhibitor that can suppress cancer cell survival by inducing apoptosis (Apoptosis). Its IC50 values are 51.0 nM for HEK293T, 9.2 nM for A549, 5.2 nM for MCF-7, 8.9 nM for MGC-803, and 35.4 nM for PC-3M cells. Additionally, YSY01A eliminates constitutive STAT3 signaling by downregulating gp130 and JAK2 in human A549 lung cancer cells. YSY01A holds promise for research in the field of cancer therapy.
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- CAS No.: 1194235-46-5
- Formule: C29H38BN5O5
- Masse moléculaire:547.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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IL6-beta |
JAK2 |
Stat-3 |
Chemical Information
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CAS No. 1194235-46-5
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Masse moléculaire 547.45
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Formule C29H38BN5O5
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SMILES
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=CC=C2)C2=C1)C(N[C@H](B(O)O)CC(C)C)=O)=O)C3=CN=CC=N3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)