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Art. -Nr.: HY-183534

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CDK2-IN-58

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research.

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CAS. Nr.: 328061-33-2
Formel: C₁₈H₁₅N₅
Molecular Weight:301.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK2-IN-58 Chemical Structure

CAS. Nr.: 328061-33-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research^[1].

IC₅₀ & Target^[1]

CDK2

0.21 μM (IC₅₀)

Alle CDK Isoform-spezifische Produkte anzeigen :

In Vitro

CDK2-IN-58 (Compound 1a) inhibits CDK2-cyclin E enzyme activity with an IC₅₀ of 0.21 μM in a cell-free scintillation proximity assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 328061-33-2
Molecular Weight 301.35
Formel C₁₈H₁₅N₅
SMILES

N1=CC=C(N=C1NC=2C=CC=CC2)C3=C(N=C4C=CC=CN43)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Byth KF, et al. Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett. 2004 May 3;14(9):2245-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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CDK2-IN-58

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CDK2-IN-58 Related Classifications

HY-183534 Related Classifications