EZH2-IN-15
Based on 1 publication(s) in Google Scholar
EZH2-IN-15 is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.18%
- CAS. Nr.: 2098545-98-1
- Formel: C32H44N4O4
- Molecular Weight:548.72
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) EZH2-IN-15
MoreAlle Histone Methyltransferase Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 2098545-98-1
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Appearance Solid
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Molecular Weight 548.72
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Formel C32H44N4O4
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Color Off-white to yellow
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SMILES
O=C1NC(C)=CC(C)=C1CNC(C2=C3C=C(CN4CCCCC4)OC3=CC(N(C5CCOCC5)CC)=C2CC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Death Dis
EZH2 inhibitor SHR2554 enhances the anti-tumor efficacy of HDAC inhibitor Chidamide through STAT1 in T-cell lymphoma. [Abstract]2025 Jul 14;16(1):522. PMID: 40659662
Lösungsmittel & Löslichkeit
DMSO : 125 mg/mL (227.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8224 mL | 9.1121 mL | 18.2242 mL | 45.5606 mL |
| 5 mM | 0.3645 mL | 1.8224 mL | 3.6448 mL | 9.1121 mL | |
| 10 mM | 0.1822 mL | 0.9112 mL | 1.8224 mL | 4.5561 mL | |
| 15 mM | 0.1215 mL | 0.6075 mL | 1.2149 mL | 3.0374 mL | |
| 20 mM | 0.0911 mL | 0.4556 mL | 0.9112 mL | 2.2780 mL | |
| 25 mM | 0.0729 mL | 0.3645 mL | 0.7290 mL | 1.8224 mL | |
| 30 mM | 0.0607 mL | 0.3037 mL | 0.6075 mL | 1.5187 mL | |
| 40 mM | 0.0456 mL | 0.2278 mL | 0.4556 mL | 1.1390 mL | |
| 50 mM | 0.0364 mL | 0.1822 mL | 0.3645 mL | 0.9112 mL | |
| 60 mM | 0.0304 mL | 0.1519 mL | 0.3037 mL | 0.7593 mL | |
| 80 mM | 0.0228 mL | 0.1139 mL | 0.2278 mL | 0.5695 mL | |
| 100 mM | 0.0182 mL | 0.0911 mL | 0.1822 mL | 0.4556 mL |
EZH2-IN-15 Related Classifications
HY-153191 Related Classifications
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