Sulfameter
Based on 2 publication(s) in Google Scholar
Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.94%
- CAS. Nr.: 651-06-9
- Formel: C11H12N4O3S
- Molecular Weight:280.30
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Anti-Infection Compound Library
HY-L002
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Publications Citing Use of MedChemExpress (MCE) Sulfameter
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Biologische Aktivität
Sulfameter forms a complex with silver, which shows activity against both Gram-positive bacteria (such as S. aureus) and Gram-negative bacteria (such as E. coli and P. aeruginosa), but it is more active against Gram-negative bacteria[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 651-06-9
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Appearance Solid
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Molecular Weight 280.30
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Formel C11H12N4O3S
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Color White to off-white
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SMILES
O=S(C1=CC=C(N)C=C1)(NC2=NC=C(OC)C=N2)=O
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Synonyms
Sulfametoxydiazine; 5-Methoxysulfadiazine; NSC 683528
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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ACS Omega
Identification of New Modulators and Inhibitors of Palmitoyl-Protein Thioesterase 1 for CLN1 Batten Disease and Cancer. [Abstract]2024 Feb 28;9(10):11870-11882. PMID: 38496939 -
ACS Omega
Using Bibliometric Analysis and Machine Learning to Identify Compounds Binding to Sialidase-1. [Abstract]2021 Jan 20;6(4):3186-3193. PMID: 33553934
Lösungsmittel & Löslichkeit
DMSO : ≥ 100 mg/mL (356.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (8.92 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (8.92 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5676 mL | 17.8380 mL | 35.6761 mL | 89.1902 mL |
| 5 mM | 0.7135 mL | 3.5676 mL | 7.1352 mL | 17.8380 mL | |
| 10 mM | 0.3568 mL | 1.7838 mL | 3.5676 mL | 8.9190 mL | |
| 15 mM | 0.2378 mL | 1.1892 mL | 2.3784 mL | 5.9460 mL | |
| 20 mM | 0.1784 mL | 0.8919 mL | 1.7838 mL | 4.4595 mL | |
| 25 mM | 0.1427 mL | 0.7135 mL | 1.4270 mL | 3.5676 mL | |
| 30 mM | 0.1189 mL | 0.5946 mL | 1.1892 mL | 2.9730 mL | |
| 40 mM | 0.0892 mL | 0.4460 mL | 0.8919 mL | 2.2298 mL | |
| 50 mM | 0.0714 mL | 0.3568 mL | 0.7135 mL | 1.7838 mL | |
| 60 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4865 mL | |
| 80 mM | 0.0446 mL | 0.2230 mL | 0.4460 mL | 1.1149 mL | |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3568 mL | 0.8919 mL |
Sulfameter Related Classifications
HY-B0213 Related Classifications
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